research Ketoconazole-p Aminobenzoic Cocrystal Exhibits a Potent Anti-inflammatory Effect on the Skin of BALBc Mice
The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.
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390-420 / 1000+ results research MOESM1 of A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse
research Determination of Cystine and Cysteine in Altered Human Hair Fibers
Cold waving solutions quickly reduce cystine to cysteine in hair.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research 085 Coordinate expressions of cyclin-dependent kinase inhibitors and high sulfur protein in human hair follicles
research β-Catenin is involved in oleanolic acid-dependent promotion of proliferation in human hair matrix cells in an in vitro organ culture model
Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
research Impact of acid (”progressive brush”) and alkaline straightening on the hair fiber: Differential effects on the cuticle and cortex properties
Glyoxylic acid straighteners cause more protein loss but have similar hair strength effects as traditional alkaline straighteners.
research Investigation of pH effect on cationic solute binding to keratin and partition to hair
Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.
research B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy
Boron/nitrogen-doped carbon nano-onions improve targeted breast cancer treatment by enhancing drug delivery and reducing side effects.
research Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion
Charge-conversion chemistry improves hair-rebonding by enhancing penetration and strength.
research Biotin and biotinidase deficiency
Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
research Low Serum Biotinidase Activity in Children with Valproic Acid Monotherapy
Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
research The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research Two novel BTD mutations causing profound biotinidase deficiency in a Chinese patient
The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
research Ichthyosis follicularis with alopecia and photophobia syndrome with coexisting palmoplantar keratoderma treated with acitretin
A girl with a rare skin condition improved after one month of treatment with acitretin.
research The formulation and in‐vitro evaluation of WS Biotin, a novel encapsulated form of D‐Biotin with improved water solubility for hair and skin treatment applications
WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
research Inhibitory amino acid transmitters associated with axons in presynaptic apposition to cutaneous primary afferent axons in the cat spinal cord
Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
research Mechanism of hair straightening
Hair can be straightened using different chemicals, not just strong alkali.
research Circumventing Mukaiyama oxidation: selective S–O bond formation via sulfenamide–alcohol coupling
A new, efficient method creates sulfinimidate esters from sulfenamides and alcohols without metals.
research Dissimilar effects of the hydrophilic carbon dots on the amyloid aggregation of two model proteins and the mechanism discussion
Hydrophilic carbon dots cause one protein to clump more and prevent another from clumping.
research 085 Post-translational regulation of hair keratins in transfected COS-1 cells
research Molecular modeling and structural characterization of a high glycine–tyrosine hair keratin associated protein
The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
research Glycoconjugate expression of cells of human anagen hair follicles during keratinization
Human anagen hair follicles have unique carbohydrate patterns during keratinization.
research Diagnosis and treatment of methylmalonic acidemia in 14 cases
Early diagnosis and proper treatment improve outcomes for methylmalonic acidemia.
research Enhanced substantivity of hyaluronic acid on keratin substrates via polymer complexation
Polymer complexation makes hyaluronic acid stick to hair better, enhancing its moisturizing effects.
research Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses
Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
research Sequences and differential expression of three novel human type-II hair keratins
Hair differentiation starts earlier than thought, involving multiple type-II keratins.