research OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
Search
for
Sort by
Research
240-270 / 1000+ results 
research PROTECTIVE EFFECT OF TRIBULUS TERRESTRIS ON HEPATO-BIOCHEMICAL PARAMETERS OF ALBINO RAT AFTER TREATMENT WITH DRUG CYPROTERONE ACETATE
Tribulus terrestris may protect the liver from drug damage.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Polycystic Ovary Syndrome and Cardiovascular Disease
PCOS increases the risk of heart disease and type 2 diabetes in women.
research The Osler Lecture 2012 'Pharmacology 2.0, medicines, drugs and human enhancement'
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
research Minoxidil in severe hypertension: Value when conventional drugs have failed
Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
research Ultrasonographic and laboratory markers of metabolic and cardiovascular disease risk in obese women with polycystic ovary syndrome
Obese women with PCOS are more likely to have fatty liver disease.
research LabeledIn: Cataloging labeled indications for human drugs
Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
research Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research Effect of non-steroidal anti-inflammatory drugs on post-surgical complications against the backdrop of the opioid crisis
NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
research Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome
High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Beyond Hormones: A Systematic Review of the Risk of Cardiovascular Diseases in Polycystic Ovary Syndrome
Women with PCOS have a higher risk of heart disease due to factors like insulin resistance and obesity.
research Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers
Human hair protein modifications could potentially indicate heart disease risk.
research Anabolic androgenic steroids impact on cardiovascular risk and cardiovascular events. The literature review
Anabolic-androgenic steroids increase the risk of heart problems.
research Microneedles: A Promising Therapeutic Strategy for Next-Generation Drug Delivery, Diagnosis and Biosensing
Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
research COVID-19: How Effective Are the Repurposed Drugs and Novel Agents in Treating the Infection?
Vaccination is the most effective way to reduce COVID-19 transmission.
research Possible contribution of chronobiology to cardiovascular health
Understanding and tracking our body's natural daily rhythms could help improve heart health.
research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome (PCOS): A Six-Month, Open-Label Randomized Study
Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
research Alopecia and its association with coronary heart disease and cardiovascular risk factors: A meta-analysis
People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
research Using a capture–recapture method to assess the frequency of adverse drug reactions in a French university hospital
The study found that combining different databases gives a better estimate of drug side effects in hospitals.
research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Lipid Profile, Atherogenic Index of Plasma, and Anthropometric Measurements Among Osteoporotic Postmenopausal Sudanese Women: Possible Risk for Cardiovascular Disease
Osteoporotic postmenopausal Sudanese women have a high risk of cardiovascular disease.
research TREATMENT OF SEVERE ALOPECIA AREATA USING METHOTREXATE AS AN ADJUNCTIVE DRUG IN COMBINATION WITH INTRAVENOUS AND ORAL CORTICOSTEROID
Methotrexate with corticosteroids can help regrow hair in severe alopecia areata but may cause relapses and side effects.
research Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms
Natural products might help treat hair greying.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.