research A review on computer‐aided chemogenomics and drug repositioning for rationalCOVID ‐19 drug discovery
Computer-aided methods can speed up COVID-19 drug discovery and help find new uses for existing drugs.
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720-750 / 1000+ resultsresearch A review on computer‐aided chemogenomics and drug repositioning for rational
research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Analyzing Big EHR Data—Optimal Cox Regression Subsampling Procedure with Rare Events
A new method makes analyzing large datasets with rare events faster and more efficient.
research New approach to 3-oxo-4-aza-5α-androst-1-ene-17β-(--butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
research Quantifying hair shape and hair damage induced during reshaping of hair.
New imaging and testing methods can effectively assess hair shape changes and damage.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Accessing Properties of Molecular Compounds Involved in Cellular Metabolic Processes with Electron Paramagnetic Resonance, Raman Spectroscopy, and Differential Scanning Calorimetry
These methods help understand cell structures and reactions.
research Mouse tail skin wholemount staining and intravital calcium imaging
The method helps study hair follicle stem cells and calcium signals in mouse skin.
research Applications of Trace-Element and Stable-Isotope Geochemistry to Wildlife Issues, Yellowstone National Park and Vicinity
Geochemical methods help manage wildlife by revealing toxic elements and diet details in Yellowstone.
research Scanning electron microscopes/silicon drift detector-energy dispersive spectroscopy: An analytical tool to identify waterborne microminerals pickup in human scalp hair cuticle due to water quality
The method can identify minerals in hair from water, and using coconut oil or conditioner can prevent mineral buildup.
research Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer
Non-invasive methods can effectively monitor skin inflammation and cancer biomarkers.
research From bench to babies – drug development for male subfertility
New methods may speed up drug development for male subfertility.
research Liquid chromatography-mass spectrometry for simultaneous determination of spironolactone and canrenone in plasma samples
A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.
research Cells to Surgery Quiz: April 2020
Certain surgical methods are better than routine incision for hidradenitis suppurativa, topical clindamycin and acitretin are effective treatments, men with HS have a risk of skin cancer, HS patients are more likely to die from heart problems, and specific genetic markers are linked to treatment response.
research 612 Targeted hair follicle delivery of hydrophilic molecules
Researchers developed a new method to deliver molecules to hair follicles to manage hair growth without damaging surrounding skin.
research Role of tissue expansion in hair restorative surgery
Tissue expansion is a safe primary method for hair restoration in patients with large scalp defects before hair transplantation.
research 단삼과 황금의 추출방법을 달리한 세포증식 효과 및 항산화 활성효과 연구
Ethanol and ultrasonic wave extraction methods are best for making effective cosmetics and anti-hair loss products.
research Assessing the effect of cleansing products on artificially polluted human hairs and skin through in vivo and in vitro models
New methods effectively measure how well hair products clean and protect against pollution.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research Flexible label-free SERS substrate with alginate-chitosan@silver nanocube for in situ nondestructive detection of thiram on apples
A new method was developed to detect pesticide residues on apples without damage.
research Nanoscale microenvironment engineering for expanding human hair follicle stem cell and revealing their plasticity
A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
research Simultaneous Determination of Selected Steroids with Neuroactive Effects in Human Serum by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry
A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
research Emerging biomedical engineering strategies for hair follicle regeneration
New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
research Hair removal using a pulsed-intense light source.
Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research Genetic Fate Mapping Using Site-Specific Recombinases
The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development
A new method, iSiMPRe, effectively identifies key protein regions in cancer genes, highlighting potential drug targets.
research Colorimetric assay for γ-glutamyl transpeptidase
The document concludes that measuring γ-glutamyl transpeptidase activity is more accurate with a higher substrate concentration and using diluted acetic acid to stop the reaction.
research Three‐dimensional imaging and analysis of the surface of hair fibres using scanning electron microscopy
The new 3D imaging method accurately measures hair surface details quickly.