November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
February 2023 in “Vaccines” COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
Natural products may help treat hair loss by promoting hair growth with fewer side effects.
1 citations
,
May 2024 in “Applied Sciences” Cordyceps militaris is a promising, cost-effective medicinal fungus with health benefits and efficient production methods.
October 2025 in “Biomedicines” Terminalia chebula fruit extract helps hair growth by reducing DHT and boosting hair cell activity.
1 citations
,
January 2022 in “Springer eBooks”
September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
1 citations
,
September 2023 in “Life science alliance” Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
236 citations
,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
17 citations
,
August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
8 citations
,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
July 2010 in “British Journal of Dermatology” New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.
49 citations
,
October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
211 citations
,
April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
183 citations
,
January 2014 in “BioMed Research International” AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
119 citations
,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
106 citations
,
June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
95 citations
,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
49 citations
,
October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
47 citations
,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
44 citations
,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
41 citations
,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
20 citations
,
February 2017 in “International Journal of Dermatology” Honokiol helps protect skin from damage and aging caused by cigarette smoke.