September 2023 in “Biomedical Optics Express” New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Both induced and spontaneous AA lymphocytes can cause alopecia areata in mice.
34 citations
,
June 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
January 2011 in “Kufa Medical Journal” Minoxidil solution applied on skin can effectively promote hair growth and increase hair thickness in male mice.
3 citations
,
April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
71 citations
,
January 1998 in “Pathobiology” The document concludes that certain rats and mice are useful for studying hair loss in humans and testing treatments.
2 citations
,
August 2016 in “Journal of Investigative Dermatology” 3 citations
,
March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.
20 citations
,
April 2000 in “Experimental dermatology” ODC transgenic mice can model human hair loss with skin lesions.
Spiny mice have resilient, large mitochondria that help them regenerate tissue.
101 citations
,
August 2001 in “The Journal of Cell Biology” A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.
October 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
3 citations
,
April 2012 in “Fertility and Sterility” Finasteride may cause infertility in rats by affecting epididymis and sperm function.
19 citations
,
March 2003 in “Journal of Investigative Dermatology” Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
23 citations
,
June 2017 in “Rejuvenation Research” Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.
34 citations
,
January 2008 in “Developmental Biology” 8 citations
,
August 2022 in “BMC Veterinary Research” C57BL/6 mice and SD rats have different sweat gland and hair follicle patterns, useful for skin research.
18 citations
,
April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.
18 citations
,
August 2018 in “The FASEB journal” Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
March 2025 in “International Journal of Molecular Sciences” The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.
5 citations
,
March 2022 in “STAR Protocols” The method helps study hair follicle stem cells and calcium signals in mouse skin.
6 citations
,
August 2001 in “PubMed” The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
10 citations
,
November 2008 in “Veterinary Dermatology” The mouse hairy ears mutation causes longer ear hair due to changes in gene expression.
A new image-based method improves accuracy in measuring hair loss in mice.
53 citations
,
October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
January 2020 in “ScholarWorks (Central Washington University)” NAG-1 may help prevent some metabolic issues related to PCOS.
8 citations
,
January 2015 in “Clinical and Experimental Dermatology” A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.
22 citations
,
October 2004 in “Journal of Investigative Dermatology” The gene causing hair loss and heart issues in rough coat mice is still unknown.
7 citations
,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.