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Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.

PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

CS12192 effectively treats alopecia areata with better safety than current options.

Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.

CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

JAK/STAT1 pathway causes hair loss during chemotherapy by reducing Shh in hair follicles.

Knocking out certain genes in mice helps understand skin and hair growth problems.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

AR-27 E-Chol siRNA can effectively promote hair regrowth for androgenetic alopecia.

Suppressing ODC activity reduces tumor growth in hair follicles.

The HCR gene contributes to psoriasis risk.

Ablative fractional laser treatment nearly matches the gene reduction effects of topical vismodegib in skin cancer.

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

LGD1069 effectively prevents breast tumors in mice without toxicity.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

A defective gene causes hair loss and taste insensitivity in BTBR mice.

Deleting part of a gene in mice causes wavy hair and high pup loss.

Researchers made a mouse model with curly hair and hair loss by editing a gene.

AR-27 E-Chol siRNA can effectively regrow hair by reducing androgen receptor gene activity.

A new genetic tool improves the study of hair growth and potential hair disorder treatments.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.