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A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer

research A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer

January 2025 in “Recent Patents on Anti-Cancer Drug Discovery”

The treatment showed high response rates and was well-tolerated, potentially extending patient survival.

research 004 Cell-based therapy may be effective in alopecia areata: Preclinical evidence that autologous, peripheral regulatory γdT cells are preventive in human ex vivo and therapeutic in human in vivo models

November 2022 in “Journal of Investigative Dermatology”

Cell-based therapy using specific immune cells may help treat alopecia areata by promoting hair regrowth.

research O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion

July 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

HPV8 E6 gene causes growth of certain skin stem cells.

research Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch

8 citations , August 2014 in “Biochemical and Biophysical Research Communications”

ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.

research PRC 2 preserves intestinal progenitors and restricts secretory lineage commitment

75 citations , September 2016 in “EMBO journal”

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

research Connexin 30, a new marker of hyperproliferative epidermis

18 citations , July 2006 in “British Journal of Dermatology”

Connexin 30 is usually absent in normal skin but can appear in certain skin conditions.

research FOXN1 deficient nude severe combined immunodeficiency

32 citations , January 2017 in “Orphanet journal of rare diseases”

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

research Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway

January 2026 in “Stem Cell Research & Therapy”

ASLNC168501 can help treat hair loss by restoring hair follicle stem cell function.

research Four murine monoclonal antibodies specific for the inner root sheath in the human hair follicle

1 citations , January 1989

Four antibodies were developed to help study hair follicle cell differentiation.

Clinical Snippets: Insights into Dermatological Studies

research Clinical Snippets

January 2016 in “Journal of Investigative Dermatology”

Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.

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