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Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor-β (TGF-β)/Mesenchymal Stem Cells (MSCs) Balance: A Complex Partnership in Skin Rejuvenation

research Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation

1 citations , January 2019 in “Journal of Embryology & Stem Cell Research”

MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.

Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells

research Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells

5 citations , January 2021 in “iScience”

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

research LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway

4 citations , May 2024 in “Cytotechnology”

research Differentiation of CD34+ Human Hair Follicle Stem Cells into Functional Melanocytes

1 citations , December 2018 in “IOP conference series. Materials science and engineering”

CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.

research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin

5 citations , May 2023 in “Frontiers in Cell and Developmental Biology”

Integrin α6 helps identify different neural crest cell types in the skin.

research 131 Mutational landscape of extramammary Paget disease

April 2018 in “Journal of Investigative Dermatology”

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

CD27 and IL-35 as Diagnostic Biomarkers in Alopecia Areata: First Evidence of Association with Pathogenic Scalp Bacterial Infections

research CD27 and IL-35 as diagnostic biomarkers in alopecia areata: First evidence of association with pathogenic scalp bacterial infections

December 2025 in “Babcock University Medical Journal”

CD27 and IL-35 can help diagnose alopecia areata linked to bacterial infections.

research ISID0602 – Efficacy of autologous cell-based therapy for male and female pattern hair loss using dermal sheath cup cells: A single arm, multi-center, confirmatory clinical study.

May 2023

research A Murine Monoclonal Antibody (VM-1) Against Human Basal Cells Inhibits the Growth of Human Keratinocytes in Culture

25 citations , April 1985 in “Journal of Investigative Dermatology”

research Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation

16 citations , April 2024 in “Proceedings of the National Academy of Sciences”

HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.

Dual Aspects of B Cells in Tumor Immunity: Positive and Negative Regulation Against B16 Melanoma

research Dual aspects of B cells in tumor immunity; B cells are capable of positive and negative regulation for tumor immunity against B16 melanoma

April 2017 in “Journal of Dermatological Science”

B cells can both help and hinder the body's defense against melanoma.

research Conversion of C57Bl/6 mice from a tumor promotion-resistant to a -sensitive phenotype by enhanced ornithine decarboxylase expression

31 citations , September 1999 in “Molecular Carcinogenesis”

Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.

Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

research Data from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

March 2023

Activating certain hair follicle cells could prevent hair loss from cancer treatments.

research CPC12 Coinheritance of BRCA2 and CYLD germline pathogenic variants associated with targetable metastatic malignant cylindroma

June 2023 in “British Journal of Dermatology”

Coinheritance of BRCA2 and CYLD genes may lead to new treatment options for certain cancers.

research Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells

37 citations , October 2009 in “Veterinary Dermatology”

Canine hair follicles contain stem-like cells with high growth potential.

research Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

88 citations , August 1998 in “Carcinogenesis”

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

research K6/ODC transgenic mice as a sensitive model for carcinogen identification

57 citations , July 2000 in “Toxicology Letters”

K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.

research 083 More Expression of IL-17 than IFN-γ from CD49a-negative Tissue-Resident Memory T (Trm) cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients according to the Foxp3+mTregs depletion

September 2019 in “Journal of Investigative Dermatology”

IL-17 and certain immune cells are linked to more severe alopecia areata.

research HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion

25 citations , June 2017 in “Journal of Investigative Dermatology”

HPV8 causes skin cancer by expanding specific skin stem cells.

research CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

28 citations , April 2024 in “Immunity”

CD80 on skin stem cells helps expand Treg cells to aid wound healing.

research High throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in Alopecia Areata

1 citations , November 2018 in “immuneACCESS”

Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.

research Molecular and Functional Characterization of Clonogenic Human Thymic Epithelial Cells

January 2012 in “Infoscience (Ecole Polytechnique Fédérale de Lausanne)”

Human thymus has stem cells that can self-renew and maintain their identity.

research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms

68 citations , November 2011 in “The American journal of pathology”

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

research Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function

10 citations , November 2023 in “Science Immunology”

Super-enhancers control CD25 expression in specific cell types, affecting immune function.

research O 17-6 Carcinome améloblastique mandibulaire

September 2005 in “Revue de Stomatologie et de Chirurgie Maxillo-faciale”

research The diagnostic algorithm in pre-invasive cervical lesions

2 citations , October 2021 in “Journal of Mind and Medical Sciences”

Early screening and HPV vaccination reduce cervical cancer risk.

research Decision‐Making Regarding the Administration of Live Vaccines to Patients With a FOXN1 Heterozygous Missense Variant

January 2026 in “Pediatrics International”

Live vaccines can be safely given to infants with a FOXN1 variant if their immune function improves over time.

research Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13

51 citations , December 2006 in “Mammalian Genome”

research Colon Cancer Stem Cells: Promise of Targeted Therapy

411 citations , April 2010 in “Gastroenterology”

Targeting colon cancer stem cells might lead to better treatment results.

research Image2.TIF

December 2021

GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.

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