research Resident macrophages of the lung and liver: The guardians of our tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
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600-630 / 1000+ results research Dual In Situ Integration for Braided Silk Fibers Enabling Multifunctional Bioactive Sutures
The new silk suture with silver and curcumin helps heal wounds faster and fights bacteria.
research Generation of functionally active resident macrophages from adipose tissue by 3D cultures
3D cultures can create active macrophages from fat tissue.
research A transcriptomic map of murine and human alopecia areata
Alopecia areata involves specific immune cells, offering potential treatment targets.
research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
research Human adipose tissue-derived small extracellular vesicles promote soft tissue repair through modulating M1-to-M2 polarization of macrophages
Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
research Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
research Antibody Drug Conjugates
Antibody drug conjugates show promise in targeting cancer cells while reducing harm to healthy cells.
research In This Issue
Genetically repaired stem cells may treat certain genetic diseases, Th17 cells are key in fighting systemic fungal infections, hair loss in AGA is due to progenitor cell loss, and α-synuclein transfer might contribute to Parkinson's disease progression.
research Recurrent pseudolymphomatous reaction to ear piercing: 20-year history
A woman had a rare reaction to ear piercing that caused earlobe swelling, which was best treated by removing the piercing and not re-piercing.
research Leukemia cutis of the scalp masquerading as 'Kerion' in a child
Leukemia can sometimes appear as unusual skin issues in children.
research Reprogramming Wound Healing: GAG ‐Based Bioactive Scaffold Drives Pro‐Regenerative Cellular Cross‐Talk
The scaffold improves wound healing and tissue regeneration.
research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
research Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research EMT Factors and Metabolic Pathways in Cancer
EMT and metabolic pathways help cancer cells resist treatment and spread.
research The Role of Hair Follicle Immune Privilege Collapse in Alopecia Areata: Status and Perspectives
Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
CDK4/6 inhibitors can protect hair cells from chemotherapy damage.
research The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris
Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.
research The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications
Alopecia areata severity and treatment response are linked to specific cytokine levels.
research Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis
Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.
research Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles
Targeting Vδ1+T-cells may help treat alopecia areata.
research Genomic Regions Associated with Wool, Growth and Reproduction Traits in Uruguayan Merino Sheep
Certain genes influence wool, growth, and reproduction traits in Uruguayan Merino sheep.
research Report from the Cicatricial Alopecia Colloquium
More research is needed to understand and treat cicatricial alopecias.
research EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression
The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
research A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia
The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis
Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
research Thymic stromal lymphopoietin controls hair growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research Minoxidil Nanoparticles Targeting Hair Follicles Enhance Hair Growth in C57BL/6 Mice
Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.
research Tissue Engineering and Regeneration of the Human Hair Follicle in Androgenetic Alopecia: Literature Review
Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
research From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology
JAK inhibitors are effective for treating moderate-to-severe alopecia areata.