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GlossaryCD34+ cells

stem cells in blood and bone marrow with CD34 protein

CD34+ cells, also known as CD34 positive cells, are a type of stem cell found in the blood and bone marrow that have the CD34 protein on their surface. These cells are crucial for the formation of blood cells and are often used in medical treatments like bone marrow transplants to regenerate the blood and immune system.

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Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells

235 citations , January 2011 in “Journal of Clinical Investigation”

Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.

research The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study

88 citations , December 2012 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

54 citations , January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

research CD34 ⁺ cell–derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis

39 citations , April 2023 in “Science Advances”

CD34⁺ cells help heal damaged limbs by promoting blood vessel growth.

research CD34 glycoprotein identifies putative stem cells located in the isthmic region of canine hair follicles

21 citations , July 2006 in “Veterinary dermatology”

CD34 marks potential stem cells in dog hair follicles.

research Participation of CD34-enriched mouse adipose cells in hair morphogenesis

16 citations , February 2013 in “Molecular Medicine Reports”

CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.

research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration

2 citations , May 2019 in “Advances in wound care”

Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.

research Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture

2 citations , June 2022 in “Scientific reports”

Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.

research Therapeutic efficacy of TriCell CD34+ cell-containing, platelet-rich plasma in alopecia patients

June 2020 in “Journal of cosmetic medicine”

TriCell CD34+ cell-containing PRP therapy improves hair thickness and density in alopecia patients without side effects.

research Immunohistochemical Pattern of CD34 Distribution in Different Types of Basal Cell Carcinoma and in Peritumoral Skin

January 2026 in “Medicina”

CD34 is absent in most basal cell carcinoma cells but present in surrounding skin.

research CD34 and BerEP4 Are Helpful to Distinguish Basaloid Tricholemmoma From Basal Cell Carcinoma

6 citations , March 2018 in “The American journal of dermatopathology/American journal of dermatopathology”

BerEP4 and CD34 staining can help tell apart tricholemmoma from basal cell carcinoma.

research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34

561 citations , April 2003 in “Journal of Investigative Dermatology”

CD34 is a marker for isolating stem-like cells in mouse hair follicles.

research CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties

41 citations , April 2019 in “PLOS genetics”

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

research Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation

13 citations , October 2020 in “Journal of Neural Transmission”

CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.

research In vitro neural differentiation of CD34 + stem cell populations in hair follicles by three different neural induction protocols

18 citations , October 2014 in “In vitro cellular & developmental biology. Animal”

Hair follicle stem cells can become neural cells using different methods, with varying efficiency.

research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium

4 citations , January 2016 in “Methods in molecular biology”

Hair follicle stem cells can become nerve cells using specific treatments.

research Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 induces proliferation of CD34+ hair follicle stem cell

January 2017 in “Seoul National University Open Repository (Seoul National University)”

AIMP1 can boost hair growth by increasing stem cell activity.

Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

research Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

11 citations , September 2019 in “Dermatologic Surgery”

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

Faculty Opinions Recommendation of Bald Scalp in Men With Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Faculty Opinions recommendation of Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.

April 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Bald men with male pattern baldness still have hair stem cells, but lack certain cells needed for hair growth.

research Faculty Opinions recommendation of Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.

January 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Bald men with male pattern baldness still have hair stem cells, but lack certain cells needed for hair growth.

research Faculty Opinions recommendation of Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.

January 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Bald men with male pattern baldness still have hair stem cells, but lack certain cells needed to grow hair.

research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice

141 citations , May 2007 in “Cancer Research”

CD34 is crucial for skin tumor development in mice.

research Differentiation of CD34+ Human Hair Follicle Stem Cells into Functional Melanocytes

1 citations , December 2018 in “IOP conference series. Materials science and engineering”

CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.

research Differential diagnosis of basal cell carcinoma and benign tumors of cutaneous appendages originating from hair follicles by using CD34.

13 citations , January 2010 in “PubMed”

research Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia

88 citations , July 2019 in “International Journal of Molecular Sciences”

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss

56 citations , May 2017 in “Nature Cell Biology”

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

52 citations , February 2012 in “PloS one”

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

research Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers

33 citations , March 2013 in “Journal of Investigative Dermatology”

Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.

New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology

research New developments in stem cell biology and therapy. meeting report from the working group of the German Society for Hematology and Oncology

5 citations , January 2005 in “Cytotherapy”

The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.

research There and Back Again: Hair Follicle Stem Cell Dynamics

4 citations , January 2011 in “Cell stem cell”

Hair follicle stem cells can return to their original niche and help regenerate hair.