419 citations
,
March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
319 citations
,
November 2005 in “Proceedings of the National Academy of Sciences” Hair follicle stem cells can help repair damaged nerves.
144 citations
,
June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
106 citations
,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
89 citations
,
May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
88 citations
,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
54 citations
,
December 2014 in “Wound Repair and Regeneration” PRP injections may improve hair thickness and density in female hair loss patients.
53 citations
,
April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
37 citations
,
October 2009 in “Veterinary Dermatology” Canine hair follicles contain stem-like cells with high growth potential.
35 citations
,
December 2008 in “PubMed” Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
33 citations
,
March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
28 citations
,
February 2014 in “Journal of Cutaneous Pathology” Keratoacanthoma changes as it grows, showing different hair follicle characteristics at each stage.
28 citations
,
June 2012 in “International Journal of Molecular Medicine” Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.
25 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
25 citations
,
January 2013 in “Journal of Cell Science” Tenascin-C and tenascin-W help control stem cell movement and growth in whisker follicles.
23 citations
,
September 2013 in “Molecular Carcinogenesis” Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
20 citations
,
March 2014 in “PubMed” Hair follicle stem cell research has advanced in understanding and using these cells for hair growth and skin repair.
20 citations
,
December 2013 in “PTR. Phytotherapy research/Phytotherapy research” Ginsenoside Rg3 may help hair growth by increasing a growth-related protein in hair cells.
20 citations
,
April 2009 in “Cell Biology International” Hair follicle stem cells can become corneal-like cells with the help of pax6.
19 citations
,
August 2019 in “Journal of Cellular Biochemistry” ADSCs help protect skin from UV damage and aging.
19 citations
,
January 2014 in “International Journal of Medical Sciences” Abnormal activation of hair follicle stem cells and Wnt/β-catenin signaling contributes to sebaceous neoplasms.
17 citations
,
January 2013 in “Journal of Cutaneous Pathology” The onychodermis helps anchor the nail bed and may aid in nail formation.
14 citations
,
June 2012 in “Stem Cells” TACE/ADAM17 is essential for maintaining healthy hair and hair follicle stem cells.
13 citations
,
May 2017 in “Current Protocols in Stem Cell Biology” A method was developed to isolate and study hair follicle stem cells from mouse skin.
13 citations
,
April 2016 in “Journal of Visualized Experiments” The method successfully isolates hair follicle stem cells and skin cells from mice for research.
13 citations
,
September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
12 citations
,
January 2018 in “PubMed” Y-27632 helps hair follicle stem cells grow and keep their abilities.