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ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.

Alopecia areata involves unique activation of certain immune cells.

PCFCL may have unrecognized subtypes and needs more research.

Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.

848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.

Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.

The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.

Injecting specific cells into the skin can help improve skin structure and reduce blisters in a genetic skin disorder.

Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.

CDH3-related disease causes worsening eye and hair issues.

Deleting part of a gene in mice causes wavy hair and high pup loss.

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

TCDD reduces EGF receptor activity and causes various developmental changes in animals.

CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.

Tmem30b is essential for hearing by maintaining hair cell structure in the ear.

Trodelvy™ helped some patients with advanced breast cancer, but had side effects.

Alopecia areata involves immune system changes, especially in severe cases, with potential new treatment targets identified.

Ritlecitinib may help treat alopecia areata by protecting hair follicles.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

CD90 is abundantly present on stem-like cells in dog hair follicles.

DAB labeling effectively identifies collagen type III and PDGFR in horse skin, but may show false positives.