research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus
Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
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research Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia
The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research Human Teeth Is Useful Even after Its SHED! So, Why Discard It?
Baby teeth stem cells can potentially grow organs and treat diseases.
research Entdeckung von Autoantigenen bei der Haarverluststörung Alopecia areata: Implikation von posttranslationalen Modifikationen
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research 097 LFA-1 blockade prevents the onset of alopecia areata in C3H/HeJ mice
Blocking LFA-1 prevents hair loss in mice.
research Human ClinicalPhenotype Associated with FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways
Similar treatments might work for different types of scarring hair loss.
research Intranasal sensitization model of alopecia areata using pertussis toxin as adjuvant
Pertussis toxin may contribute to hair loss in alopecia areata.
research Cemiplimab-Induced Alopecia Areata
A man developed temporary hair loss after taking a cancer drug, which might indicate a better treatment response.
research Neuroimmunoendocrine circuitry of the ‘brain-skin connection’
Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
research Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases
Stat3 helps skin heal but can also cause skin diseases if overactive.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Actinic keratosis: a clinical and epidemiological revision
Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
research Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes
TRPV3 in skin cells causes inflammation and cell death.
research The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
research Blocking Potassium Channels (Kv1.3): A New Treatment Option for Alopecia Areata?
Kv1.3 blockers may help treat alopecia areata and promote hair regrowth.
research The extracellular matrix dictates regional competence for tumour initiation
The extracellular matrix affects where tumors can start in the body.
research Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Acne: Transient Arrest in the Homeostatic Host–Microbiota Dialog?
Acne is a temporary skin imbalance during puberty that often resolves on its own.
research Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss
Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
research Risk of autoimmune diseases in patients with RASopathies: systematic study of humoral and cellular immunity
Patients with RASopathies are at risk for autoimmune disorders and should be routinely screened.
research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
research The Therapeutic Role of ADSC-EVs in Skin Regeneration
ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
research Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo
Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.
research Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Role of regeneration in tissue repairing and therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect
Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
research Dermal lymphatic dilation in a mouse model of alopecia areata
Mice with alopecia areata had wider lymphatic vessels in their skin.