September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
127 citations
,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
18 citations
,
July 2014 in “Molecular Medicine Reports” UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
8 citations
,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
5 citations
,
October 2024 in “International Journal of Biological Sciences” A peptide from hair follicle stem cells can boost hair growth.
June 2026 in “Frontiers in Cell and Developmental Biology” Dermal papilla cells are key to fine wool growth in sheep.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
22 citations
,
April 2020 in “Scientific reports” Changthangi goats have specific genes that help produce Pashmina wool.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
479 citations
,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
341 citations
,
November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
224 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
209 citations
,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
172 citations
,
May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
124 citations
,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
117 citations
,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
101 citations
,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
82 citations
,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
70 citations
,
October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
67 citations
,
December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
35 citations
,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.