1 citations
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December 2010 in “Elsevier eBooks” Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
September 2025 in “Institutional Repositories DataBase (IRDB)” The nanoemulsion system effectively delivers drugs through the skin and shows promise for treating skin conditions.
March 2024 in “Research Square (Research Square)” Sex steroids affect the MafB gene differently in male and female hamsters.
September 2022 in “Institutional Repositories DataBase (IRDB)” 3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
16 citations
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January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
341 citations
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November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
98 citations
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July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
82 citations
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March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
70 citations
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March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
61 citations
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September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
60 citations
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July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
54 citations
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April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
46 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
35 citations
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October 2017 in “Trends in Molecular Medicine” Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
33 citations
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April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
30 citations
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October 2010 in “Journal of The American Academy of Dermatology” The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.
27 citations
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December 2014 in “Current problems in dermatology” Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.
26 citations
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May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
20 citations
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
18 citations
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July 2014 in “Molecular Medicine Reports” UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
15 citations
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June 2015 in “Human Cell” Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
14 citations
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April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
13 citations
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December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
13 citations
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March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
12 citations
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August 2022 in “Stem cell reviews and reports” Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
11 citations
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July 2017 in “Regenerative Medicine” The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.