36 citations
,
February 2017 in “Journal of Cellular and Molecular Medicine” VEGF165 helps hair follicle stem cells become blood vessel cells, aiding new blood vessel growth.
33 citations
,
March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
24 citations
,
November 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.
15 citations
,
September 2018 in “Applied Biological Chemistry” Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.
11 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
10 citations
,
June 2022 in “Frontiers in Immunology” Fucoidan reduces bone cell formation by affecting T-cell activity.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” The research identified genes that explain why some sheep have curly wool and others have straight wool.
8 citations
,
December 2022 in “BMC Genomics” The research improved understanding of yak hair growth to help use yak wool better.
1 citations
,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
February 2026 in “Advanced Science” TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
August 2025 in “Stem Cell Research & Therapy” Exosomes from stem cells can help regrow hair better than minoxidil.
January 2025 in “PLoS ONE” ING5 is crucial for stem cell maintenance and preventing certain cancers.
April 2024 in “The Indonesian Biomedical Journal” Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.
133 citations
,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
26 citations
,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
January 2026 in “Stem Cell Research & Therapy” ASLNC168501 can help treat hair loss by restoring hair follicle stem cell function.
January 2026 in “International Journal of Molecular Sciences” S100a4 is key for hair growth in cashmere goats.
140 citations
,
December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
135 citations
,
October 2010 in “Stem Cells” Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.
133 citations
,
June 1993 in “Molecular and Cellular Biology” The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.
128 citations
,
February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
98 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Keratin gene regulation is similar across mammals, affecting hair follicle differentiation.
64 citations
,
February 2008 in “Cancer Research” Inactivating both p53 and Rb genes in mice speeds up aggressive skin cancer development.
37 citations
,
February 2007 in “Experimental Dermatology” Increasing PDCD4 protein may help prevent or treat some skin cancers.
19 citations
,
September 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” Glucocorticoid receptors help regulate genes important for skin health and hair growth.
19 citations
,
July 1964 in “PubMed” Hair follicle cells become four types: medulla, cortex, cuticle, and inner root sheath.