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GlossaryStem Cell Markers

specific proteins identify and distinguish stem cells from others

Stem cell markers are specific proteins or molecules found on the surface of stem cells that help identify and distinguish them from other cell types. These markers are crucial for researchers and clinicians to isolate, study, and potentially use stem cells in therapies, including treatments for hair loss and alopecia.

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research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

52 citations , February 2012 in “PloS one”

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

research Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments

28 citations , March 2010 in “Histochemistry and Cell Biology”

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

research Recent progress in hair follicle stem cell markers and their regulatory roles

13 citations , February 2024 in “World Journal of Stem Cells”

New markers help understand and use hair follicle stem cells for regeneration.

research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

54 citations , January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors

9 citations , January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

April 2024 in “Communications biology”

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

27 citations , October 1998 in “Differentiation”

Basonuclin helps identify and track hair follicle development and cycling in mice.

research Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata

6 citations , March 2011 in “European Journal of Dermatology”

Nestin-positive cells are important for hair follicle regeneration in alopecia areata.

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

January 1998 in “Differentiation”

Basonuclin is crucial for hair follicle development and cycling in mice.

research Effects of Natural Herbal Marker Compounds on Human Dermal Papilla Cell Growth Regulation

December 2023

Four natural compounds were found to promote hair growth effectively.

research The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

207 citations , July 2006 in “Development”

MTS24 marks a new type of skin cell that helps hair growth and repair.

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

96 citations , July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

LRIG1 as a Positive Prognostic Marker in Merkel Cell Carcinoma and Expression of Epithelial Stem Cell Markers

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

10 citations , July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

LRIG1 is linked to better survival in Merkel cell carcinoma.

Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Near the Distal End of the Arrector Pili Muscle

research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle

5 citations , January 2016 in “Stem Cells International”

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.

35 citations , December 2008 in “PubMed”

Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.

Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

research Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata

20 citations , December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

research From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.

8 citations , January 2021 in “PubMed”

Hair follicle stem cells may help treat acute pancreatitis by reducing inflammation and aiding regeneration.

research Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties

5 citations , February 2023 in “Frontiers in Veterinary Science”

Ovine dermal papilla cells are promising for hair growth research due to their stable properties and hair-inducing abilities.

research 1361 A novel cell surface marker for hair follicle dermal cells throughout hair morphogenesis and cycling

April 2018 in “Journal of Investigative Dermatology”

Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.

research Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200

12 citations , November 2007 in “Journal of Investigative Dermatology”

CD200 is not a reliable marker for identifying stem cells in all skin types.

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

6 citations , September 2009 in “European journal of histochemistry”

CD90 is present on specific cells in dog hair follicles.

research Re-Assessing K15 as an Epidermal Stem Cell Marker

36 citations , March 2011 in “Stem Cell Reviews and Reports”

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

15 citations , September 2009 in “European Journal of Histochemistry”

CD90 is abundantly present on stem-like cells in dog hair follicles.

research 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds

October 2021 in “Journal of Investigative Dermatology”

DPP4, a molecule in skin, helps heal large wounds and regrow hair follicles when its levels are reduced.

research The calcium-binding protein calretinin is a marker of the companion cell layer of the human hair follicle

26 citations , June 2005 in “British Journal of Dermatology”

Calretinin identifies the companion cell layer in human hair follicles.

Nestin as a Marker of Unipotent Epithelial Progenitor Cell Differentiation into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles

research Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles

May 2022 in “Research Square (Research Square)”

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

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Related Terms

Research

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

research Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments

research Recent progress in hair follicle stem cell markers and their regulatory roles

research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors

research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

research Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata

research Basonuclin as a cell marker in the formation and cycling of the murine hair follicle

research Effects of Natural Herbal Marker Compounds on Human Dermal Papilla Cell Growth Regulation

research The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle

research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.

research Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata

research From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.

research Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties

research 1361 A novel cell surface marker for hair follicle dermal cells throughout hair morphogenesis and cycling

research Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

research Re-Assessing K15 as an Epidermal Stem Cell Marker

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

research 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds

research The calcium-binding protein calretinin is a marker of the companion cell layer of the human hair follicle

research Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles

research A preliminary study of markers for human hair follicle melanin stem cell

research Ber‐EP4 antigen is a marker for a cell population related to the secondary hair germ

research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34

research Keratins in health and cancer: more than mere epithelial cell markers