174 citations
,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
5 citations
,
September 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
13 citations
,
February 2025 in “Nature Communications” A new neural network helps identify key regulators in cell changes, aiding in understanding diseases and finding new treatments.
38 citations
,
April 2017 in “PLOS Genetics” GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
75 citations
,
June 2007 in “Journal of Biological Chemistry” MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
23 citations
,
March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
23 citations
,
September 2013 in “Molecular Carcinogenesis” Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
1 citations
,
April 2024 in “Cells” Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin 15 helps keep skin cells in a young, undifferentiated state.
April 2023 in “Journal of Investigative Dermatology” ALRN-6924 can protect hair follicles from chemotherapy damage by temporarily stopping cell division.
October 2021 in “Research Square (Research Square)” Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.
3 citations
,
June 2013 in “Genes & development” CaV1.2 helps activate hair follicle stem cells without calcium flux.
December 2024 in “Drug Discoveries & Therapeutics” Baricitinib-loaded EVs help hair regrowth in alopecia areata by reducing inflammation and promoting hair follicle regeneration.
141 citations
,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
October 2021 in “Research Square (Research Square)” Melatonin affects certain genes and pathways involved in cashmere goat hair growth.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
February 2022 in “Journal of Investigative Dermatology” Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
16 citations
,
October 2018 in “Experimental Dermatology” Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
68 citations
,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
10 citations
,
February 2019 in “Journal of cellular physiology” TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
13 citations
,
June 2020 in “International Journal of Molecular Sciences” HNG helps hair grow by keeping hair in the growth phase longer.
August 2025 in “Aesthetic Plastic Surgery” Collaboration and innovation are key to developing effective, safe hair loss treatments.
31 citations
,
December 2022 in “Cold Spring Harbor Perspectives in Biology” Understanding cell transitions can lead to better wound healing treatments.
April 2019 in “Journal of Investigative Dermatology” Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
June 2023 in “SPIRE - Sciences Po Institutional REpository” Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.
August 2016 in “Journal of Investigative Dermatology” Human hair follicles have a scent receptor that can influence hair growth.
June 2021 in “DOAJ (DOAJ: Directory of Open Access Journals)” JAK inhibitors show promise for treating alopecia areata but their effectiveness and safety are still debated.
25 citations
,
October 1975 in “Journal of Cutaneous Pathology” Hair growth in alopecia areata is hindered due to impaired cell activity in the surrounding tissue.