118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
42 citations
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January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
50 citations
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December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
150 citations
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May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
January 2026 in “International Journal of Molecular Sciences” S100a4 is key for hair growth in cashmere goats.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
36 citations
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November 1990 in “The Journal of Dermatology” Dermal papillae enhance hair follicle growth and structure.
June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
February 2010 in “Journal of the American Academy of Dermatology” Activating cAMP and ATP improves hair growth and strength.
April 2023 in “ACS Biomaterials Science & Engineering” 3D scaffolds mimicking the extracellular matrix are crucial for effective hair follicle regeneration.
10 citations
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November 2020 in “American Journal Of Pathology” Integrin β1 is crucial for liver structure and function, preventing fibrosis.
22 citations
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October 2007 in “Journal of Investigative Dermatology” Stem cells in mouse nails are found in the nail matrix and may control nail growth.
2 citations
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May 2018 in “Journal of Investigative Dermatology” Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.
June 1967 in “Journal of Cellular Physiology” The 3D hair follicle model improves understanding of hair growth and drug testing.
66 citations
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August 1990 in “Journal of Investigative Dermatology” Epithelial cell growth in rat hair follicles needs contact with mesenchymal cells through the extracellular matrix.
64 citations
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August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
19 citations
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January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
14 citations
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July 2019 in “Journal of Investigative Dermatology” Integrin-linked kinase is crucial for melanoblasts to properly colonize the skin.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
13 citations
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July 2019 in “PLoS ONE” Deleting podoplanin in mice promotes hair growth by enhancing cell migration.
172 citations
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March 2019 in “The EMBO Journal” FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.
December 2016 in “Paleontological Journal” Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
41 citations
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July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
73 citations
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August 2019 in “Cell Proliferation” Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.
11 citations
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June 2017 in “Mathematical Medicine and Biology A Journal of the IMA” The model helps understand and improve treatments for alopecia areata by simulating hair growth and immune cell interactions.
Wound healing involves three phases and various cells and factors, with scars typically forming in adults. Chronic wounds can occur due to various issues, and abnormal scarring can lead to hypertrophic or keloid scars. Emerging research areas include the role of proteins, microRNAs, macrophage manipulation, and stem cell treatment.
27 citations
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December 1997 in “Archives of Dermatological Research” Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
6 citations
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September 2007 in “PubMed” Stem cell niches regulate the number and function of stem cells in the body.
9 citations
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March 2023 in “Biomimetics” New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.