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Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Targeting TRP channels may help reduce excessive scarring.

Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.

Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The HATMSC1 cell line from fat tissue can produce helpful factors for regenerative and immune therapies.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.

Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Skin issues can indicate immune system problems.

Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.

Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

PLA2R1 overexpression harms kidney cells by stopping their growth cycle.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.

Plant root hair growth is controlled by the hormone auxin, which affects the production of certain oxygen-related molecules through a specific process.

Dithranol reduces inflammation in alopecia areata by lowering certain immune responses.

Acne is a temporary skin imbalance during puberty that often resolves on its own.

The immune processes causing VKH and vitiligo are similar in dogs and humans.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.