June 2026 in “Open Access Research Journal of Biology and Pharmacy” This study investigates potential multi-target drugs against Onchocerca volvulus, a major cause of blindness in developing regions. Using molecular docking simulations, 2,015 approved drugs were screened against glutamate S-transferase and prolyl tRNA synthetase. Bedaquiline and Telmisartan showed the strongest binding affinities, while Diosmin, Azelastine, and Adapalene were identified as promising multi-target drugs based on molecular dynamics. Other compounds like Drospirenone, Alectinib, Dutasteride, and Finasteride also showed potential. The study suggests repurposing these drugs could offer effective treatments for onchocerciasis, with further validation needed.
March 1997 in “Fertility and sterility” Finasteride is an effective and well-tolerated treatment for hirsutism.
21 citations
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April 2011 in “Epilepsia” The drug combination significantly reduced epileptic drop attacks in patients.
October 2004 in “Australian Prescriber” Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.
February 2026 in “International Journal of Dermatology” Ritlecitinib shows promise in improving hair regrowth in adolescents with alopecia areata.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
9 citations
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
February 2025 in “Buletin Veteriner Udayana” Ivermectin and sulfur effectively treated the cat's scabies and sporotrichosis in 14 days.
26 citations
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January 2014 in “ALTEX” Pesticides can cause reproductive and adrenal health issues.
1 citations
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March 2025 in “Acta fytotechnica et zootechnica/Acta fytotechnica et zootechnica” Quercetin may help improve skin conditions in cats with Feline Atopic Skin Syndrome.
1 citations
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September 2024 in “Veterinary Medicine and Science” Afoxolaner effectively treats mange in guinea pigs with one dose.
January 2021 in “Clinical dermatology open access journal” Dermatologists in Western Rajasthan often prescribe doxepin for elderly patients with skin and mental health issues.
17 citations
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January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
3 citations
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April 1977 in “PubMed” The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.
4 citations
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September 2014 in “Elsevier eBooks” Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.
6 citations
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December 1996 in “The Journal of Clinical Pharmacology” Terazosin and finasteride together cause no major issues.
8 citations
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January 2025 in “Gels” The developed nasal gel improves cilostazol delivery to the brain, enhancing its effectiveness and reducing side effects.
27 citations
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October 2020 in “Drugs” Clascoterone cream was approved in the USA for treating acne in people aged 12 and older.
4 citations
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July 2023 in “Nature Medicine” The FDA approved a new Pfizer drug for hair loss in teens.
March 2022 in “International Journal of Trichology” Tofacitinib may be effective for treating hair loss caused by alopecia areata that doesn't respond to other treatments.
November 2024 in “SKIN The Journal of Cutaneous Medicine” Ritlecitinib provides new treatment options for diverse alopecia areata patients.
7 citations
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September 2013 in “Current Dermatology Reports” Some skin medications are safe for pregnant women, but others pose risks or should not be used.
1 citations
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June 2022 in “International Journal of Infectious Diseases” A fungal infection was successfully treated with oral and topical antifungals after being misdiagnosed and worsened by corticosteroids.
2 citations
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June 2019 in “Boletín médico del Hospital Infantil de México” Tofacitinib treatment is used for teenagers with alopecia areata.
24 citations
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January 2007 in “The FASEB Journal” Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.
5 citations
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January 2007 Citrullus colocynthis extracts may promote hair growth as effectively as minoxidil.
13 citations
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November 2021 in “Pediatric Dermatology” Tofacitinib taken by mouth helps treat hair loss in children.
4 citations
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January 2014 in “Vegetos” Ziziphus is a versatile plant with health benefits and commercial uses.
December 2024 in “Cureus” Tirzepatide improved symptoms and hair regrowth in a man with folliculitis decalvans.
May 2024 in “Reactions weekly” January 2024 in “Arquivos de Neuro-Psiquiatria” Both new medications and non-drug treatments can effectively manage migraines with fewer side effects.