research The Diagnostic Value of Free Androgen Index in Obese Adolescent Females with Idiopathic Hirsutism and Polycystic Ovary Syndrome
FAI is a reliable marker for identifying and monitoring hyperandrogenism in obese adolescent females with PCOS.
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research Prediction of gain-of-function and loss-of-function mutations using Combined Annotation Dependent Depletion (CADD)
C-scores can help predict gain-of-function and loss-of-function mutations.
research Quantification of biotin in plasma samples by column switching liquid chromatography – tandem mass spectrometry
The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.
research Treatment of Cystathionine β-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
research Development of Free Testosterone Chemiluminescence Detection Kit and Its Clinical Application
The new testosterone detection kit is accurate, cost-effective, and useful for diagnosing diseases.
research Determination of finasteride in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry with flow rate gradient
Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
research 778 Designing and utilizing a c-Rel specific bioassay in drug repurposing screen for HNSCC
A new test helps find drugs to treat head and neck cancer by targeting c-Rel.
research A smart deoxyribozyme-based fluorescent sensor for in vitro detection of androgen receptor mRNA
Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.
research ecancermedicalscience
Hair analysis may help detect breast cancer early by identifying changes in lipid content.
research Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure
Cell-free fat extract may boost IVF success in older women with past failures.
research A systematic method for the sensitive and specific determination of hair lipids in combination with chromatography
A new method accurately measures hair lipids, revealing individual differences.
research Testosterone-like immunoreactivity in hair measured in minute sample amounts - a competitive radioimmunoassay with an adequate limit of detection
The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
research Markers of hyperandrogenism in South Asians with polycystic ovary syndrome
The FG score is better at detecting hyperandrogenism in PCOS patients than testosterone levels or FAI, but testosterone is the recommended test for diagnosis.
research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS
A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
research Synchronous fluorescence as a green and selective method for the simultaneous determination of finasteride and tadalafil in dosage form and spiked human plasma
A new green method accurately measures finasteride and tadalafil in drugs and plasma.
research Measurement of steroid hormones by liquid chromatography-tandem mass spectrometry with small amounts of hair
A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
research Rapid high-performance liquid chromatogaphic method for detection of interindividual differences in carcinogen metabolism
Human hair follicles can assess carcinogen metabolism and imidazole compounds might be effective anticarcinogens.
research LC-MS/MS improves screening towards 21-hydroxylase deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching
New method detects finasteride in plasma quickly and accurately without clean-up.
research 268 Use of ultra-fast one-step CK5 ihc for identifying bcc and scc during mohs surgery
A new one-step test can quickly identify skin cancer during surgery.
research Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents
The method effectively measures lipid changes and drug effects on skin follicles.
research Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS)
Hair follicles can be used to study gene expression and understand conditions like COPD.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research The patch assay reconstitutes mature hair follicles by culture-expanded human cells
The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
research Hair Growth Measurement Using Intradermal Sulfur 35 Cystine
The method accurately measures hair growth with minimal risk and is better than other techniques.
research Hair growth measurement using intradermal sulfur 35 cystine
The method accurately measures hair growth with minimal risk and is better than other methods.
research Valency based novel quantitative structure property relationship (QSPR) approach for predicting physical properties of polycyclic chemical compounds
The neighborhood face index (NFI) accurately predicts properties of complex molecules.
research HPLC-APCI-MS Determination of Finasteride in Human Plasma
The method accurately measures finasteride in human plasma quickly and reliably.
research Receiver operating characteristic analysis of the performance of basal serum hormone profiles for the diagnosis of polycystic ovary syndrome in epidemiological studies
Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
research Cell‐free transcriptomic profiles and mechanism insights in female androgenetic alopecia
DNAJB9 cfRNA could help diagnose and treat female hair loss.