The document discusses how traditional Chinese medicine extracts may affect hair growth in animals but lacks detailed results.
The document concludes that most hair loss treatments don't work, balding isn't caused by dandruff, and hair loss may indicate serious health issues that require medical attention.
September 1961 in “Archives of Dermatology” Colchicine causes hair loss by damaging hair follicles.
July 2020 in “Journal of The American Academy of Dermatology” Botulinum toxin affects hair follicles, inhibiting TGF-B1 secretion; more research ongoing.
282 citations
,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
251 citations
,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
232 citations
,
June 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling helps heal injuries and could lead to new treatments.
220 citations
,
August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
184 citations
,
January 2000 in “European Urology” Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
179 citations
,
July 2005 in “Human Reproduction Update” PCOS is influenced by both genes and environment, but its exact genetic cause is still unclear.
139 citations
,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
92 citations
,
November 2003 in “The Journals of Gerontology” Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
84 citations
,
September 2014 in “European journal of endocrinology” Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.
82 citations
,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
82 citations
,
April 2008 in “Journal of Investigative Dermatology” EDA2R gene linked to hair loss.
72 citations
,
March 2013 in “Primates” More research is needed to understand how diet affects isotope signatures in Japanese macaque tissues.
56 citations
,
November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
51 citations
,
September 2008 in “Journal of Investigative Dermatology” Vitamin D receptor may help protect against UV-induced skin cancer.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics” Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
47 citations
,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
47 citations
,
March 2017 in “Clinical, cosmetic and investigational dermatology” Certain skin conditions may indicate or increase the risk of Parkinson's disease.
47 citations
,
January 2003 in “Current opinion in urology” A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
46 citations
,
February 2016 in “Experimental Dermatology” Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
46 citations
,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
45 citations
,
November 2012 The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.
44 citations
,
June 2024 in “Regenerative Therapy” PRP therapy may cause infections and other issues, needing more research for safety.
44 citations
,
December 2005 in “Journal of Investigative Dermatology” Certain genetic markers, especially the MICA gene, are linked to alopecia areata.
44 citations
,
March 2004 in “Journal of Investigative Dermatology” The effects of estrogen on human hair growth are unclear and need more research.