research Chemotherapy-induced toxicity—a secondary effect caused by released DNA?
Chemotherapy toxicity might be reduced by using DNA neutralizing agents.
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330-360 / 1000+ resultsresearch Fibroblast bioelectric signaling drives hair growth
Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
research BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development
BAF200 is essential for proper heart and coronary artery formation.
research Lamins in development, tissue maintenance and stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Ultrastructure of Follicular Mucinosis
Follicular mucinosis causes significant damage to hair follicle cells.
research Ultrastructural skin changes in Egyptian mandibuloacral dysplasia patients with p.Arg527Leu LMNA mutation and in their asymptomatic heterozygotic mothers
The LMNA mutation affects skin structure even in asymptomatic carriers.
research Activity evaluation of epidermo-melanin unit and dermal damage in melasma
Melasma results from changes in the skin's pigment and structure, not just pigment cell growth.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Oncogenic senescence: a multi-functional perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research The crest phenotype in domestic chicken is caused by a 195 bp duplication in the intron of HOXC10
A 195 bp duplication in the HOXC10 gene causes crests in domestic chickens.
research Premature aging syndromes: From patients to mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Fine structure of marsupial hairs, with emphasis on trichohyalin and the structure of the inner root sheath
Marsupial hair structure and keratin distribution are similar to placental mammals.
research Significance of RU58841 as a therapeutic agent effecting androgen receptor molecular interactions in human hair follicles.
RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
research Evaluating The Cytotoxic Effects Of Silver Nanoparticles Derived From Pogostemon Benghalensis Brum. F. Kunth. Extract On A549 Lung Cancer Cells
Silver nanoparticles from Pogostemon benghalensis may effectively fight lung cancer cells.
research The remarkable legacy of the K6/ODC mouse: mechanisms of polyamine-promoted tumorigenesis revealed
Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
research 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo
A virus protein can activate a pathway that may lead to abnormal hair follicle development.
research Recent advances in X-ray microanalysis in dermatology.
Trace elements like calcium, iron, and zinc are unevenly distributed in hair, while sulfur is even, and increased phosphorus and potassium levels are linked to skin reactions.
research H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development
H3K4me3 helps control RSPO3 to influence hair growth and development.
research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Histone demethylases can change gene expression and may be linked to diseases like cancer.
research Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.
The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.
research Probing Keratinocyte and Differentiation Specificity of the Human K5 Promoter in Vitro and in Transgenic Mice
The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.
research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells
A truncated protein linked to breast cancer may change cell adhesion.
research Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity
Runx1 and CDK inhibitors help keep hair follicle stem cells inactive, affecting their future roles.
research In Silico Promoter Motif Analysis of Human Fertility-Related Genes
The study found potential new DNA patterns in fertility genes, but further testing is needed.
research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles
research Changes in hair chromium concentrations with increasing distances from hair roots
Hair chromium levels show past nutritional status, not environmental exposure.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research 977 The wound healing of fractional photothermolysis mimicks scarless healing with minimal myofibroblast activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research 975 Antifibrogenic activities of novel vitamin D3 analogs are dependent on VDR expression in human fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.