610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
11 citations
,
October 2016 in “Pediatric dermatology” Stopping the use of fluocinolone oil containing balsam fragrance improved hair regrowth in children allergic to it.
2 citations
,
August 2024 in “JID Innovations” AD-derived keratinocytes effectively mimic inflammation in atopic dermatitis.
2 citations
,
May 2011 in “British Journal of Dermatology” Pellagra, caused by niacin deficiency and presenting with photosensitivity, should be considered in patients with relevant symptoms and risk factors.
1 citations
,
September 2022 in “Nepal journal of dermatology, venereology & leprology” Apremilast shows promise for several skin conditions but needs more research.
1 citations
,
June 2021 in “Journal of dermatology and dermatitis” Tyrosine kinase inhibitors show promise in treating some skin diseases but their definitive role in dermatology is still unclear.
March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
September 2025 in “Frontiers in Immunology” Atopic dermatitis and alopecia areata share immune and genetic factors, and targeted therapies may help both.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
August 1996 in “Australasian Journal of Dermatology” The document concludes that "Photodamage" and "Photoimmunology" are valuable resources, while "Pediatric Dermatopathology" and "Hair and Scalp Disorders" have limitations.
50 citations
,
August 2021 in “Stem Cell Research & Therapy” Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
223 citations
,
September 2018 in “Rheumatology” JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
157 citations
,
August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
132 citations
,
July 2000 in “Lupus” In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
96 citations
,
March 2003 in “Life Sciences” Atopic dermatitis patients have much higher acetylcholine levels in their skin, which may cause itching.
89 citations
,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
74 citations
,
July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
67 citations
,
September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
64 citations
,
January 2004 in “American journal of clinical dermatology” Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.
63 citations
,
March 1998 in “Archives of Dermatology” Antidepressants may improve or resolve scalp dysesthesia in most patients.
48 citations
,
October 1996 in “Dermatologic clinics” Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
47 citations
,
September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
39 citations
,
January 2011 in “Archives of Dermatology” Reflectance confocal microscopy confirms that yellow dots are signs of damaged hair follicles in alopecia areata.
34 citations
,
August 2005 in “Dermatologic Clinics” Stress and emotional factors can worsen skin conditions by affecting the immune system.
25 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” Alopecia areata significantly lowers quality of life, especially in personal and social areas, and more so if the patient is also depressed.
21 citations
,
September 2016 in “Journal of Dermatological Treatment” The new classification system for skin disorders emphasizes the importance of understanding a patient's awareness of their condition for better treatment.
19 citations
,
April 2018 in “International Journal of Dermatology” People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.
18 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
17 citations
,
July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.