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A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.

Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.

The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

Lipid nanoparticles improve treatment delivery and are key to future therapies, but challenges in manufacturing and safety remain.

IPM enhances skin penetration of hydrophilic drugs.

Plant and algal lipid droplets are promising for natural oil production but need better extraction methods.

Microemulsions could improve how drugs are delivered and absorbed in the body.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Cholesterol helps hair grow by activating nerves and boosting hair follicle stem cells.

Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.

Chitin nanofibrils are better at stabilizing oil droplets in emulsions than cellulose nanofibrils.

The intestinal lymphatic system is active and promising for targeted drug delivery and therapies.

Exosomes from fat stem cells can reduce fat cell formation.

Deleting MPZL3 increases skin oil production and reduces body fat.

Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.

A very-low-calorie diet led to more weight loss and health improvements in obese women with PCOS than a moderate energy deficit diet.

Adipocytes have diverse roles in energy storage, protection, tissue repair, and influence health and disease.

PCOS is linked to chronic low-grade inflammation, but the role of certain infections is unclear.

Most adult women with PCOS in Port Harcourt, Nigeria, have high levels of bad fats in their blood, especially younger women.

Women with PCOS have significant metabolic issues like insulin resistance after eating a high-fat meal.

Patients with acne and insulin resistance have different blood metabolites compared to those with only acne, which could help in diagnosis and treatment.

Modified liposomes with exosomes effectively deliver RNA to stem cells.

Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.

Psoriasis, acne, and hair loss are linked to unhealthy cholesterol levels, increasing heart disease risk.