56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
44 citations
,
September 2012 in “Archives of Dermatology” Hair breakage may be an early sign of a hair loss condition called CCCA in African American women.
37 citations
,
August 2016 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.
32 citations
,
November 2011 in “International Journal of Dermatology” Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.
29 citations
,
January 2016 in “International Journal of Dermatology” Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.
29 citations
,
September 2014 in “American Journal of Dermatopathology” Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
27 citations
,
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Hair loss in black women needs more research, early intervention, and community education.
25 citations
,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
25 citations
,
September 2014 in “Dermatologic Surgery” Hair transplants can effectively treat hair loss from CCCA in African American women if there's no inflammation.
25 citations
,
September 2010 in “Journal of Cutaneous Medicine and Surgery” The study found that Central Centrifugal Cicatricial Alopecia mainly affects middle-aged African descent women, is linked to certain hair care practices and genetics, and often goes undiagnosed for years.
24 citations
,
January 2020 in “JAAD Case Reports” Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.
19 citations
,
January 2015 in “Skin appendage disorders” The report found a new type of hair loss in African-American women that affects more areas of the scalp than previously thought.
19 citations
,
August 2011 in “Archives of Dermatology” CCCA is a common scarring hair loss in African descent women, possibly linked to genetics, hair care practices, and health issues like diabetes.
15 citations
,
November 2012 in “International Journal of Dermatology” The conclusion is that hair loss from CCCA may be genetic and not solely caused by hair grooming practices.
11 citations
,
January 2022 in “Experimental Dermatology” Severe CCCA may be biologically and clinically different from milder forms.
11 citations
,
January 2013 in “Indian Dermatology Online Journal” CCCA is a common, progressive hair loss condition that may not always be linked to hair care practices and requires a biopsy for diagnosis.
9 citations
,
October 2020 in “Journal of the American Academy of Dermatology” Patients with central centrifugal cicatricial alopecia may have a higher risk of breast and colorectal cancer.
9 citations
,
July 2020 in “JAMA dermatology” Dermatoscopy can help diagnose CCCA without visible hair loss, offering a less invasive option than biopsy.
6 citations
,
August 2022 in “Dermatologic therapy” PRP therapy can temporarily grow hair in CCCA patients but isn't a permanent cure.
6 citations
,
December 2018 in “The American Journal of Dermatopathology” Early shedding of the inner root sheath in noninflamed hair follicles is a relatively specific sign of Central Centrifugal Cicatricial Alopecia.
5 citations
,
January 2024 in “JID Innovations” CCCA involves immune response and metabolism issues, suggesting new treatment options.
5 citations
,
November 2023 in “Journal of Investigative Dermatology” 5 citations
,
April 2023 in “Life” CCCA affects adolescents too, with genetic and environmental links, requiring careful diagnosis.
3 citations
,
February 2024 in “JAAD International” Younger age, longer disease duration, frequent wig use, and lower education levels worsen quality of life in CCCA patients.
3 citations
,
April 2022 in “Cutis” CCCA is a common, scarring hair loss in Black women that needs early detection.
3 citations
,
February 2022 in “Journal of the American Academy of Dermatology” Black patients with a specific type of hair loss have a much higher chance of lacking enough vitamin D.
3 citations
,
August 2020 in “PubMed” Some natural ingredients like onion juice, rosemary oil, and pumpkin seed oil may help with hair growth and reducing hair loss.
3 citations
,
April 2018 in “Journal of Investigative Dermatology” CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
2 citations
,
January 2025 in “JAAD Case Reports” Topical metformin may improve hair regrowth in CCCA when added to standard treatments.
2 citations
,
September 2023 in “Journal of the European Academy of Dermatology and Venereology” Trichoscopy is a useful tool for diagnosing different types of female hair loss without needing a biopsy.