Wound healing involves three phases and various cells and factors, with scars typically forming in adults. Chronic wounds can occur due to various issues, and abnormal scarring can lead to hypertrophic or keloid scars. Emerging research areas include the role of proteins, microRNAs, macrophage manipulation, and stem cell treatment.
PRP shows promise for treating cicatricial alopecia but needs more research.
29 citations
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January 2016 in “International Journal of Dermatology” Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.
3 citations
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April 2022 in “Cutis” CCCA is a common, scarring hair loss in Black women that needs early detection.
March 2025 in “International Journal of Trichology” Janus kinase inhibitors may effectively treat resistant scalp conditions like folliculitis decalvans and dissecting cellulitis.
4 citations
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May 2023 in “Composites Part B: Engineering” The nanocomposite hydrogels can repair themselves, change shape, reduce inflammation, protect against oxidation, kill bacteria, stop bleeding, and help heal diabetic wounds while allowing for wound monitoring.
4 citations
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August 2010 in “Journal of the American Academy of Dermatology” Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
January 2013 in “Health Medicine Research and Practice” Cissus repens ointment helps heal burns effectively.
3 citations
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September 2018 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) can improve hair loss in cicatricial alopecia cases, but treatment must be ongoing and results vary among patients.
1 citations
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July 2012 in “Nasza Dermatologia Online” CCCA may be caused by both hair traction and an immune response.
8 citations
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September 2016 in “The American Journal of Dermatopathology” Enlarged sweat gland ducts may indicate scarring hair loss.
January 2024 in “Journal of Medicine in Scientific Research” Adding PRP to hair transplants improves results and recovery for patients with scarring hair loss.
14 citations
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May 1987 in “Archives of Dermatology” Tissue expansion is an effective treatment for certain types of hair loss, providing immediate coverage with hair-bearing skin.
1 citations
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October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
March 2021 in “CRC Press eBooks” Microneedling helps improve skin and hair by creating tiny, controlled skin injuries.
February 2024 in “International journal of medical science and clinical research studies” CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.
17 citations
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October 2024 in “Journal of the American Academy of Dermatology” Brepocitinib effectively reduces inflammation and improves symptoms in cicatricial alopecia with good safety.
March 2026 in “Journal of Investigative Dermatology” Genetic factors, especially PADI3 gene variants, contribute to CCCA in women of African descent.
September 2025 in “Cureus” There is no standard treatment for CCCA, and practices vary widely.
August 2021 in “Al-Azhar International Medical Journal (Print)” Hair transplantation is effective for treating cicatricial alopecia with fewer anesthesia risks, scars, and recovery time.
September 2024 in “JAMA Dermatology” Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.
10 citations
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January 2022 in “Journal of Research in Pharmacy” Cotinus coggygria extract cream may help heal burn wounds.
January 2016 in “Frontiers in Bioengineering and Biotechnology” Honey applied to wounds speeds up healing and improves tissue repair.
98 citations
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May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
25 citations
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October 2020 in “BMC Veterinary Research” Ivermectin cream speeds up wound healing and reduces scarring.
11 citations
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January 2013 in “Indian Dermatology Online Journal” CCCA is a common, progressive hair loss condition that may not always be linked to hair care practices and requires a biopsy for diagnosis.
49 citations
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January 2018 in “Theranostics” The new skin patch with human matrix and antibiotic improves wound healing.
65 citations
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November 2016 in “Journal of The American Academy of Dermatology” The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.
January 2026 in “Plastic & Reconstructive Surgery Global Open” Stem cell serum can regrow eyebrow hair in chronic cases and prevent hair loss if used early after trauma.
1 citations
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July 2012 in “Springer eBooks” The document concludes that more research is needed to better understand and treat scarring hair loss conditions.