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Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.

Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.

Transgender individuals face more barriers and less autonomy in surgical body modifications compared to cisgender individuals.

Testosterone increases hair growth and acne in transgender men.

Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.

Minoxidil can help transgender males grow facial hair before starting testosterone therapy.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Transgender patients on masculinizing hormones have higher hair loss rates than cisgender women.

Denying transgender minors gender-affirming care, while allowing it for cisgender minors, is sex discrimination.

Social rejection can harm long-term mental health in transgender individuals.

Gender-diverse people face more depression and anxiety, partly due to stress and lower cortisol levels.

Testosterone treatment may affect heart response to stress in transgender men.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Dermatologists should guide transgender patients on effective hair growth and loss treatments during hormone therapy.

Lip feminization is important for transgender women, requiring personalized approaches and expert consultation for best results.

Transgender patients on hormone therapy experience more acne and hair loss, but less skin inflammation.

Gender-diverse individuals face more depression and anxiety, possibly due to unique stress profiles.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Progesterone may help trans women with breast development and health, but more research is needed.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Personalized hair loss treatments are needed for transgender individuals, but more research is required.

Dermatopathologists must consider both birth sex and gender identity to accurately diagnose and treat transgender patients.