A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
January 2010 in “HAL (Le Centre pour la Communication Scientifique Directe)” Magnesium and caspase inhibitors help protect hearing after gunshot noise.
October 2025 in “PLoS ONE” Age-related hearing loss involves cochlear damage and metabolic changes.
January 2024 in “Wiadomości Lekarskie” Steroid treatment helps preserve hearing in cochlear implant patients.
October 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging reduces hair cell size and function in mice, contributing to hearing loss.
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January 2007 in “Annals of Internal Medicine” Folic acid might help with age-related hearing loss.
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April 2000 in “The Laryngoscope” Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
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January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
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July 2020 in “JAMA Dermatology” People with alopecia areata may have a higher risk of hearing loss.
September 2021 in “Research Square (Research Square)” Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
May 2010 in “OPAL (Open@LaTrobe) (La Trobe University)” Vaccines and targeting TrxR variants can help prevent cancer and reduce metastasis.
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September 1996 in “Archives of Dermatological Research” 6 citations
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January 1995 in “Equilibrium Research” Birds can regenerate inner ear hair cells from supporting cells, and mammals show potential for similar regeneration.
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November 1992 in “Journal of dermatology” Hair cells grown in a lab showed specific hair proteins.
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December 2025 in “Stem Cell Research & Therapy” Stem cell-derived exosomes can help repair ear damage and improve balance and hearing.
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January 2000 in “Acta Oto-Laryngologica” Epidermal growth factor increases extra hair cells in newborn rat ears.
April 2023 in “Research Square (Research Square)” Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
January 2008 in “Journal of Practical Medical Techniques” Microencapsulated cells can regenerate hair follicles in rat ears.
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October 1989 in “PubMed” Optimized conditions and specific treatments enhance the growth of hair cells from C3H mice.
March 2006 in “Chinese journal of plastic surgery” Microencapsulated human hair cells can regenerate hair follicles in mice ears.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The model can effectively test gene functions and drug responses in human skin.
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February 2009 in “Chinese Journal of Traumatology (english Edition)” Human hair cells can be used to grow new hair on rat ears, suggesting a possible treatment for hair loss.
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February 2025 in “International Journal of Molecular Sciences” Enzymatic digestion is an efficient method for isolating cells from hair follicles for tissue-engineered skin.
June 2017 in “International Journal of Periodontics & Restorative Dentistry” Using skin grafts from behind the ear for oral surgery in two patients with jaw injuries led to successful healing and good results.
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January 2013 in “Frontiers in Neuroanatomy” Zebrafish can help study and develop treatments for hearing loss.
January 2006 in “Chinese Journal of Dermatology” Hair follicle-like structures can be created using hair cells on collagen/chitosan scaffolds.
The model explains how mammal ear hair cells respond to sound and adapt.