19 citations
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September 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become smooth muscle cells using specific growth factors.
7 citations
,
June 2009 in “Journal of the European Academy of Dermatology and Venereology” Basement membrane changes in lichen planopilaris cause scarring and permanent hair loss.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Not having enough cystatin M/E protein causes less hair growth and dry skin.
24 citations
,
July 2019 in “Cochrane library” Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
13 citations
,
June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.
September 2023 in “Research Square (Research Square)” TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
April 2017 in “Journal of Investigative Dermatology” HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
January 2005 in “Journal of Cutaneous Pathology” The hair erector muscle is involved in various skin conditions and disorders.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
182 citations
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May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
106 citations
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August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
65 citations
,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
55 citations
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January 2007 in “Climacteric” Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
49 citations
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May 2021 in “Medicine” Understanding skin, hair, and nails is crucial due to their complexity and impact on health.
14 citations
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May 2021 in “Marine Drugs” PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
8 citations
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June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
5 citations
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September 2013 in “BMB Reports” BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
3 citations
,
July 2024 in “Cell Proliferation” Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.
1 citations
,
August 2025 in “Frontiers in Bioengineering and Biotechnology” A 3D skin model helps study wound healing better than traditional methods.
July 2025 in “Pharmaceutics” Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.
July 2024 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.
July 2024 in “ACS Biomaterials Science & Engineering” Nanoencapsulated antibiotics are more effective in treating hair follicle infections than free antibiotics.
December 2023 in “The journal of cell biology/The Journal of cell biology” The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
January 2021 in “Veterinary research forum” A Holstein calf in Iran with a severe genetic skin disorder was euthanized due to incurable symptoms.
September 2005 in “Journal of Investigative Dermatology” Ferulic acid helps stabilize vitamins C and E for better skin protection from the sun, certain compounds may promote hair growth, atopic dermatitis patients have lower skin defense molecules, older men are more likely to get a type of skin cancer, and a substance called relaxin may prevent age-related skin thickening.
March 2024 in “Drug development & registration” Mesenchymal stem cell secretome shows promise for skin treatments but needs more human trials.
238 citations
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
53 citations
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October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.