June 2026 in “Discover Immunity.” Mesenchymal stem cells (MSCs) are promising for skin repair and rejuvenation due to their regenerative, anti-inflammatory, and immunomodulatory properties. This review highlights MSCs from neonatal sources like the placenta and umbilical cord for their availability and scalability. MSCs aid skin repair through paracrine mechanisms, enhancing collagen production, reducing inflammation, and promoting cell growth. Clinical studies, including a meta-analysis of 55 trials with 2,696 patients, show MSCs' safety and efficacy in improving wound healing and skin conditions. Despite challenges like delivery optimization and reduced efficacy over time, MSC-based therapies, including MSC-derived extracellular vesicles and biomaterial-assisted delivery, show potential in regenerative and aesthetic applications.
February 2026 in “MedScien” Mesenchymal stem cells can help delay skin aging and improve wound healing.
December 2025 in “ACS Applied Bio Materials” The aloe-collagen dressing speeds up wound healing effectively.
May 2025 in “International Journal of Trichology” The supplement improved hair health and reduced shedding in people with telogen effluvium.
March 2025 in “Frontiers in Pharmacology” The hydrogel dressing rapidly heals wounds and promotes blood clotting better than existing options.
November 2024 in “Journal of Functional Foods” AP collagen peptides improve hair elasticity and gloss.
August 2024 in “Life Science Alliance” Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
September 2023 in “International journal of biomedicine” Minoxidil might help treat acne scars by reducing collagen buildup.
June 2023 in “Research Square (Research Square)” Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
May 2022 in “Research Square (Research Square)” OBEME effectively enhances wound healing and could be a promising carrier for skin treatments.
Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
9 citations
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March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
2 citations
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January 2014 in “The Korea Journal of Herbology” Polygoni Multiflori Radix may help reduce skin aging by lowering collagenase and elastase activity.
64 citations
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August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
47 citations
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November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
44 citations
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January 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
1 citations
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June 2018 in “Ukrainian Journal of Dermatology Venerology Cosmetology” Oral collagen improves skin, nails, hair, and reduces cellulite.
July 2016 in “Cancer Research” A topical lotion helped manage hair loss from chemotherapy by affecting cell death, inflammation, and collagen, with no side effects.
May 2025 in “Acta Biomaterialia” The new microneedle treatment effectively promotes hair growth better than minoxidil.
April 2016 in “Journal of The American Academy of Dermatology” People with hair loss have low zinc levels; zinc supplements and laser therapy may help.
23 citations
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June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
11 citations
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January 2016 in “Mycoses” Human black hair is best for distinguishing between T. mentagrophytes and T. verrucosum.
6 citations
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July 2021 in “Microbial biotechnology” The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.