research Scaffolds for epithelial and hair follicle regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
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300-330 / 1000+ results research Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells
Injecting specific cells into the skin can help improve skin structure and reduce blisters in a genetic skin disorder.
research Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure
The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.
research Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus
Actin and alpha-smooth muscle actin help skin heal in mouse fetuses.
research Epidermal and hair follicle transglutaminases and crosslinking in skin
research Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo
CTHRC1 helps sweat glands recover by rebuilding nearby blood vessels.
research Distinct fibroblast lineages determine dermal architecture in skin development and repair
Two fibroblast types shape skin structure and repair differently.
research Fibroblast state switching orchestrates dermal maturation and wound healing
Fibroblast state switching is crucial for skin healing and development.
research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
research Hair follicle regeneration in vitro
Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.
research The impact of AP collagen peptides (APCPs) on hair shaft elasticity and gloss: A comprehensive analysis
AP collagen peptides improve hair elasticity and gloss.
research Selection of adult hair follicle stem cells and the effects of #beta#--catenin
A method was found to select hair follicle stem cells, and beta-catenin helps them grow and change.
research CRISPR/Cas9-mediated Generation ofCOL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
Scientists created cell lines to study a genetic skin disorder using CRISPR technology.
research 364 Mechanical forces of human dermal fibroblasts significantly decrease with age
Skin cell strength decreases significantly as we age.
research Effects of extracellular matrix on the growth characteristics of human dermal papillae cellsin vitro
Some types of extracellular matrix can change how human skin cells grow but don't affect their basic functions.
research 244 Defective maintenance of hair follicle stem cells through COL17A1 loss orchestrates the hair follicle aging program
Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.
research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures
Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
research Role of collagen VI in peripheral nerves and wound-induced hair regrowth
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
research Prospects for the use of oral collagen in the treatment of telogen effluvium
Oral collagen combined with other treatments effectively reduces hair loss and improves hair quality in telogen effluvium.
research Dynamic ultrastructural changes of the connective tissue sheath of human hair follicles during hair cycle
The connective tissue around hair follicles changes structure throughout the hair cycle.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research 130 Expression of nidogen1 in basal cell carcinoma
Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
research A randomized pilot study to compare hair follicle cell suspensions prepared using trypsin alone versus trypsin in combination with collagenase type I for transplantation in vitiligo
Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.
research Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages
Proteolytic activity in mouse skin changes with hair cycle stages, peaking in early anagen.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research Niche work when you can get it: collagen XVII and the melanocyte stem cell
Collagen XVII is crucial for preventing hair and pigmentation loss by maintaining melanocyte stem cells.
research 581 Spontaneous, Intrinsic Aging in Organ-Cultured Human Skin as Novel Ex Vivo Assay to Test Candidate Anti-Aging Actives
The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.
research Application of complex filling material consisting of autologous skin fibroblast and hair keratin in medical cosmetology
The material improved facial wrinkles and skin appearance.
research DAB-labelling for collagen type III and PDGFR as control on equine skin sections.
DAB labeling effectively identifies collagen type III and PDGFR in horse skin, but may show false positives.