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research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research shows how certain drug molecules form stable structures with polymers, which could help create new drug forms.
research Drug Repurposing: Accelerating New Therapeutic Discoveries from Old Molecules (1990 – 2025)
Drug repurposing finds new uses for old drugs quickly and cheaply.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Matrix matching in quantitative bioanalysis by LC–MS/MS a dream or a reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research The Synthesis of 2,2-BIS(1-INDOL-3-YL)Acenaphthylene-1(2)-Ones Using Nanocatalysis: Fluorescent Sensing for Cu2+ Ions
A new compound was made to detect copper ions effectively.
research Selective isomerization of α-pinene oxide to campholenic aldehyde by ionic liquid-supported indenyl-molybdenum(II)-bipyridine complexes
The process efficiently converts α-pinene oxide to campholenic aldehyde using a special catalyst, achieving high yields quickly.
research Advances in structure-based drug design targeting membrane protein markers in prostate cancer
Computational methods help design drugs targeting prostate cancer proteins.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
![Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]](/images/research/fcbeee85-f5bd-406e-936d-9134a0f200d4/small/36266.jpg)
research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt2Cl4(NH3)2{μ-HN=C(O)But}2]
A new platinum complex was made and studied, which might help fight cancer better.
research Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches
Using existing drugs for new treatments is cost-effective and safer.
research In-Depth Exploration of Chemical Constituents from Justicia procumbens L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry
132 compounds were found in Justicia procumbens L., including 77 new ones.
research Antibody Drug Conjugates
Antibody drug conjugates show promise in targeting cancer cells while reducing harm to healthy cells.
research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research QUESTIONS OF TEACHING MEDICAL BIOCHEMISTRY AS PART OF AN INTEGRATED EDUCATIONAL PROGRAM IN A MEDICAL UNIVERSITY
Integrating medical biochemistry with other subjects improves clinical problem-solving skills.
research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets
research Visible Light-Mediated Environmentally Friendly and Universally Applicable Green Chemistry for Hair Cross-Linking
The study found a green method for strengthening hair works on all hair colors and is eco-friendly.
research Drug Repurposing: Accelerating New Therapeutic Discoveries from Old Molecules (1990 – 2025)
Repurposing existing drugs can quickly and cheaply find new treatments.
research Comparison of Efficacy and Specificity in Cancer‐Targeting Prodrug Conjugates
The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.
research Topological Markers for Subcellular Chemical Mapping using TOF-SIMS
TOF-SIMS improved chemical mapping in cells, confirming gunshot residue, tracking anti-tumor drugs, and identifying molecules in mosquitoes and wounds.
research How drug repurposing can advance drug discovery: challenges and opportunities
Drug repurposing is a faster, cheaper way to develop new treatments using existing drugs.
research Chemical Safety and Technical Decision-Making in Hair Procedures: A Professional and Scientific Perspective
Scientific knowledge is crucial for safe and effective chemical hair procedures.
research Synthesis and anticancer activity evaluation of Novel 6 mercaptopurine derivatives.
Compound 1 showed promising anticancer activity.
research Comprehensive HPLC and UPLC-MS/MS Analysis for the Multi-component Detection of Hair Growth Compounds in Consumer Health Products
A reliable method was developed to detect hair growth compounds in products, ensuring safety and compliance.
research Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research The Drug Reboot: Finding New Life in Old Formulations
Repurposing existing drugs can quickly and cheaply find new treatments for diseases.
research DETERMINATION OF FINASTERIDE AND RELATED COMPOUNDS BY REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. I. CHOOSING THE MOBILE PHASE COMPOSITION
Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research A new catalyst for organic synthesis: mercuric triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research ChemInform Abstract: Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α‐Reductase Inhibitor.
A new compound may effectively inhibit the enzyme linked to BPH and hair loss.