117 citations
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November 2008 in “Drug Development and Industrial Pharmacy” Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
July 2005 in “SKINmed/Skinmed” BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.
Certain ingredients in personal care products, like formaldehyde, oxidative hair dyes, and sulfates, pose health risks and need careful review.
7 citations
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September 2024 in “Applied Microbiology and Biotechnology” Malassezia furfur lipids improve skin health at pH 6.
62 citations
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July 2022 in “Science Immunology” TREM2 macrophages and unsaturated lipids contribute to acne inflammation.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” 7DHC and BM15766 damage hair follicle structure and reduce key gene expression.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MPZL3 protein helps keep sebaceous gland size and cell growth in check.
Light fraction patchouli oil at 1.5% effectively treats dandruff and promotes hair growth.
37 citations
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January 1986 in “Carcinogenesis” ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
February 2025 in “Pharmaceuticals” Myo-inositol with magnesium effectively reduces acne and hirsutism in PCOS patients without side effects.
2 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.
30 citations
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October 2015 in “Journal of Ethnopharmacology” Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
32 citations
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January 2016 in “Development” Sebaceous lipids are crucial for keeping skin and eyes healthy in mice.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Jamogenin and other molecules may help treat hair loss by inhibiting 5-alpha reductase.
33 citations
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March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
4 citations
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January 1989 Allergic reactions to minoxidil may be due to the propylene glycol it is mixed with, not the minoxidil itself.
Cold-pressed rapeseed oil is most resistant to oxidation and certain oils may reduce chronic disease risk; consumers like the taste of pumpkin oil best.
13 citations
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January 2024 in “Cureus” Acne significantly affects both physical health and mental well-being.
1 citations
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January 2005 in “Side effects of drugs annual” The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.
10 citations
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June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
9 citations
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January 2014 in “World journal of clinical cases” Neomycin is a common cause of follicular contact dermatitis, which is treated by avoiding the allergen and using creams.
December 2025 in “Cosmetics” Nanocarriers can improve skin treatments after cancer therapy by enhancing antioxidant delivery and effectiveness.
97 citations
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September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
April 2025 in “BMC Chemistry” Thiadiazole chitosan conjugates improve hair manageability, moisture, and protection in conditioners.
1 citations
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July 2022 in “International journal of trichology” Type 3 hair oil strengthens hair more than coconut oil.
August 2021 in “Research Square (Research Square)” Borneol Essential Oil could be a natural and safe acne treatment.
November 2024 in “Journal of Investigative Dermatology” Stimulating OR10J1 can promote hair growth and may help treat hair loss.