21 citations
,
June 2009 in “Current Medical Research and Opinion” Most men with hair loss worry, try self-treatments, and delay doctor visits due to cost, uncertainty, and embarrassment.
5 citations
,
December 2012 in “PubMed” Stopping the use of the drug finasteride can improve sperm count and does not prevent normal conception, but caution is advised when trying to conceive.
2 citations
,
March 2017 in “The Australian and New Zealand journal of obstetrics and gynaecology” We need better information on how fathers' exposures affect pregnancy.
211 citations
,
April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
111 citations
,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
80 citations
,
June 2002 in “Molecular Biology of the Cell” Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
73 citations
,
June 2006 in “Animal genetics” The FGF5 gene determines hair length in dogs.
65 citations
,
September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
63 citations
,
November 2012 in “Journal of Cellular Biochemistry” Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
62 citations
,
December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
53 citations
,
January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
27 citations
,
May 2011 in “Journal of Investigative Dermatology” TCHHL1 is a protein important for hair growth, found in hair follicles.
24 citations
,
May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
23 citations
,
March 2019 in “Gene” Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.
21 citations
,
January 2023 in “The International Journal of Developmental Biology” The Wnt signaling pathway is crucial for regeneration and could help advance human medicine.
18 citations
,
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Two existing drugs may help treat COVID-19 by inhibiting a key viral protein.
6 citations
,
January 2022 in “Gene” Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
4 citations
,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” AR-27 E-Chol siRNA can effectively promote hair regrowth for androgenetic alopecia.
January 2021 in “Research Square (Research Square)” STAT3 reduces FST gene activity and cell growth, affecting hair development and wool quality.
April 2016 in “Chinese Journal of Dermatology” Wnt10b can help regenerate hair follicles.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
7 citations
,
January 2024 in “Regenerative Biomaterials” The new dressing improves chronic wound healing by preserving and releasing growth factors effectively.
93 citations
,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
69 citations
,
January 2009 in “Advances in Materials Science and Engineering” Wool keratin is reactive, biocompatible, biodegradable, and can model keratin from other sources.
59 citations
,
August 1981 in “PubMed” Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.
47 citations
,
May 2012 in “Applied Water Science” Removing trace elements from drinking water is essential for human safety.
35 citations
,
January 2000 in “Dermatology” Hair loss common in Norwegian men, affecting self-esteem and life quality.
26 citations
,
January 2005 in “PubMed” RUM-loaded SLN shows promise for treating acne and hair loss topically.