86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
86 citations
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July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
77 citations
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April 1999 in “Dermatologic Clinics” The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.
68 citations
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August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
68 citations
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July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
61 citations
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September 2020 in “Bioactive Materials” A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
58 citations
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January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
57 citations
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July 2018 in “Scientific Reports” Using adipose tissue-derived fragments improves early skin graft success.
54 citations
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July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
54 citations
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November 2001 in “Urology” The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
51 citations
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May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
49 citations
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July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
41 citations
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June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
41 citations
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June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
41 citations
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December 2008 in “Current Opinion in Ophthalmology” Certain eye surgery complications can be managed effectively, especially in patients who have used specific prostate medications.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
35 citations
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October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
29 citations
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February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
29 citations
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September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
29 citations
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January 2003 in “Dermatology” The condition called 'acute diffuse and total alopecia of the female scalp' is actually a known condition named alopecia areata incognita.
28 citations
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March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
27 citations
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August 1984 in “Experimental and Molecular Pathology”
23 citations
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March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
22 citations
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February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
20 citations
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
19 citations
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January 2007 in “Journal of medical investigation” GFP transgenic mice help study cell origins in skin grafts.