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Adding a second method to PROTACs could improve cancer treatment.

Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.

Keratin-based biomaterials are promising for wound healing, drug delivery, and nerve regeneration due to their biodegradability and biocompatibility.

CD44 signaling can help heal wounds without scars.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

5α-reductase 2 is crucial for stress response in male rats.

Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.

Fat, bone, and the brain are interconnected in regulating energy and health.

Dental pulp stem cells can help heal skin and mucosal wounds effectively.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Capsaicin offers health benefits and flavor but faces challenges in food use.

Antioxidant nanoparticles show promise for treating inflammatory diseases but need more research for safe and effective use.

Bioelectronic nanogenerators show promise for cancer treatment but need better understanding and development.

Bioinspired polymers are promising for advanced medical treatments and tissue repair.

Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.

Plant-based sensors can help in healthcare but need skilled technicians.

Ellagic acid can help treat skin issues, but its effectiveness is limited by poor absorption, so new delivery methods are being explored.

Cucurbitaceae seeds, like watermelon and pumpkin, can be used in cosmetics for skin and hair benefits.

Nutraceutical insulin-sensitizing agents may help treat skin conditions like psoriasis and acne.

Microneedles show promise for cancer diagnosis and treatment due to their minimally invasive nature and effective drug delivery.

Exosomes show promise in treating acute kidney injury by protecting and repairing kidney cells.

Resveratrol shows health benefits but faces challenges in effectiveness and regulation.

Polydopamine is promising for personalized medicine and biomedical technology due to its strong adhesion and biocompatibility.

Combining hyperthermia with natural compounds and conventional treatments improves cancer therapy effectiveness and reduces side effects.

Cytarabine can cause multiple organ toxicities, especially neurotoxicity, but better research methods are needed to fully understand and predict these effects.

Functionalized bacterial cellulose can improve medical tissue engineering.

Fibroblast growth factors could be a better, safer treatment for hair loss than current options.

Ethosomes with 30% ethanol effectively deliver dutasteride to hair follicles for treating hair loss.

Targeting gut microbiome and metabolome may help treat autoimmune skin diseases like alopecia areata.