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December 2020 in “Dermatology Archives” Systemic steroids temporarily improve severe alopecia areata in children but often lead to relapse.
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March 2003 in “Endocrine Practice” The woman's symptoms and tests suggest her adrenal glands are producing too many male hormones.
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
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September 2020 in “BMC Endocrine Disorders” Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
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The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
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December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
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April 2022 in “Journal of Chromatography B” The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
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June 2015 in “Psychoneuroendocrinology” Hair cortisol and cortisone levels increase with age, are higher in diabetics, vary by gender, decrease with frequent hair washing, and are lower in winter.
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November 2023 in “International Journal of Dermatology” Topical calcineurin inhibitors might be safer than steroids for scarring alopecia, but more research is needed.
November 2022 in “Journal of the Endocrine Society” A woman with ectopic Cushing's syndrome and COVID-19 passed away despite treatment.
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June 1975 in “Archives of Dermatology” Corticosteroid injections for hair loss can cause skin thinning.
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January 2010 in “Clinical Medicine Insights Endocrinology and Diabetes” Forearm hair has more cortisol than lower leg hair.
Combining pentoxifylline with corticosteroids improves alopecia areata treatment.
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October 2018 in “Journal of Cosmetic Dermatology” Oral pulse steroids reduce TNF-α levels, improving alopecia areata.
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January 2010 in “International Journal of Trichology” Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
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May 2003 in “PubMed” Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.
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November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.