3 citations
,
January 2020 in “PubMed” Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
4 citations
,
October 2024 in “Tissue Engineering and Regenerative Medicine” 18 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” Controlling immune responses with biomaterials can reduce scarring and improve skin regeneration.
March 2026 in “Tissue Engineering and Regenerative Medicine”
9 citations
,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
June 2026 in “Materials Today Bio” The study introduces a decellularized porcine amniotic membrane (dPAM) hydrogel, engineered using supercritical carbon dioxide, which effectively removes immunogenic components while preserving bioactive molecules crucial for skin regeneration. The hydrogel promotes angiogenesis, reduces pro-inflammatory responses, and enhances regenerative signaling in human follicle-derived dermal papilla cells, indicating its potential to influence hair follicle biology. In a UVB-induced skin inflammation murine model, the hydrogel demonstrated dual functionality by reducing early immune responses and promoting tissue repair. These findings suggest that dPAM hydrogel could serve as a bioactive platform for cutaneous repair and broader regenerative applications.
12 citations
,
October 2023 in “Tissue Engineering and Regenerative Medicine” 245 citations
,
April 2009 in “Circulation Research” CD133+ cells help heal diabetic ulcers by promoting blood vessel growth and activating Wnt signaling.
91 citations
,
March 1994 in “Journal of Investigative Dermatology”
11 citations
,
May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
10 citations
,
July 2023 in “World Journal of Stem Cells” The secretome helps protect and regenerate retinal cells by enabling communication between stem cells and retinal cells.
140 citations
,
March 2013 in “The journal of immunology/The Journal of immunology” Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.
3 citations
,
July 1996 in “Clinics in Dermatology” Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.
May 2022 in “Journal of Immunology” A parasite molecule can speed up skin healing and reduce scarring.
1 citations
,
December 2025 in “Stem Cell Research & Therapy” Mesenchymal stem cells help heal wounds by using Cx43 hemichannels to improve tissue repair.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
April 2025 in “Journal of Investigative Dermatology” Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.
21 citations
,
December 2023 in “Bioengineering & Translational Medicine” Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.
April 2018 in “Journal of Investigative Dermatology” STIM1 is essential for sweat secretion.
October 2025 in “Cell Reports” Regulatory T cells help hair growth by using the Cxcr4-Cxcl12 pathway.
M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
45 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Adhesion molecules are crucial for the development of feathers and hair.
15 citations
,
May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
14 citations
,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
71 citations
,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
175 citations
,
December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
1 citations
,
March 2023 in “International Wound Journal” CCN1 may aid wound healing, but more research with larger samples is needed.
13 citations
,
July 2020 in “Stem Cell Research & Therapy” Young donor, early passage stem cells have the highest stemness.
132 citations
,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.