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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.

The rs1128977 gene variant may affect cholesterol and body measurements.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Finasteride helps reduce pain and inflammation in animals.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.

TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Ritlecitinib is the first FDA-approved pill for treating significant hair loss in alopecia areata patients aged 12 and up.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Compound 3 protects the heart from damage by activating A1-adenosine receptors.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Cinacalcet may help treat hereditary vitamin D resistant rickets safely.

New compounds show promise as nonsteroidal treatments for hair loss.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Spironolactone is a promising alternative to antibiotics for treating acne in adult females.

5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.