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Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Higher SHBG levels are linked to less severe hair loss in women, but vitamin D levels don't seem to affect hair loss.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

SHBG may be a useful early indicator and treatment target for PCOS.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Insulin resistance is strongly linked to higher androgen levels in women with PCOS.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

COC treatment improves hormone and metabolic levels in PCOS patients.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Older men with lower levels of available testosterone are more likely to be frail.

Lower 2D:4D finger ratios in HS patients suggest prenatal hormone influence on the disease.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Care for gender-dysphoric Veterans can be improved with a consistent, team-based approach.