97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
21 citations
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July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
88 citations
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December 2003 in “Journal of Biological Chemistry” Epiprofin helps cells grow in developing teeth, hair, and limbs.
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January 1993 Trichohyalin is a versatile protein involved in hair and skin structure.
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Prss53 affects hair shape and bone development in rabbits.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
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May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.
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July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
January 2005 in “Australian viticulture” Different tissues in cows have different types of cytokeratins.
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August 2008 in “Human molecular genetics online/Human molecular genetics” A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
January 1993 in “Nihon Chikusan Gakkaiho” Trichocytic cytokeratin expression starts earlier in whiskers than in body hair during rat embryo development.
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April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
The protein's size was reduced, but more work is needed to confirm its function.
3 citations
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June 2023 in “Modern Pathology” GLI1 RNA CISH effectively identifies basal cell carcinoma but is less specific for benign follicular tumors.
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November 2022 in “Cell Death and Disease” CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.
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February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
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November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
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May 2020 in “BMC plant biology” The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.
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July 2005 in “Journal of Investigative Dermatology” Sca-1+ cells in newborn mouse skin may become fat cells.
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June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
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February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
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February 2023 in “Journal of Investigative Dermatology” Ch55 may help reduce skin scarring and fibrosis.
mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.
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May 2002 in “Oncogene”
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
The KRTAP36-1 gene affects wool quality in Chinese Tan lambs.
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June 2023 in “Journal of Nanobiotechnology” Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.
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January 2018 in “Advances in experimental medicine and biology”