research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
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research CCN2 modulates hair follicle cycling in mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Enhancing hair regeneration: Recent progress in tailoring nano-structured lipid carriers through surface modification strategies
Surface-modified nanostructured lipid carriers can improve hair growth treatments.
research A Photo-Crosslinked Casein-Tannic Acid System for Enhanced Hair Protection: A Green Chemistry Approach
A natural, eco-friendly treatment using casein and tannic acid strengthens hair by 21% while keeping it elastic.
research Patients with Compound Heterozygous Mutations in Forkhead Box N1 have a Severe Immunodeficiency while Maintaining Normal Skin and Hair Development
Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
research Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders
research Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
research 856 Topical application of newly developed pseudoceramide improved both skin and hair barrier functions
Applying pseudoceramide improved skin and hair health.
research Self-assembled tetrahedral framework nucleic acids promote hair follicle stem cell proliferation and lineage differentiation
research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Skin permeation of curcumin nanocrystals: Effect of particle size, delivery vehicles, and permeation enhancer
Smaller curcumin nanocrystals penetrate skin better, but additives and particle size affect absorption and accumulation.
research Influences of skin barrier, a nanoparticle-based vehicle and solvents on cutaneous drug delivery
Disrupting the skin barrier and using specific nanoparticles and solvents can improve drug delivery through the skin.
research Unlocking the potential of cosmetic dermal delivery with ethosomes: A comprehensive review
Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.
research Assessment on the Effects of Liposome-encapsulated Thioglycolic Acid on Hair Perming
Liposome-encapsulated thioglycolic acid improves hair perming effectiveness and durability.
research Stem Cells and Their Niches
Understanding stem cell interactions with their environments is key for advancing regenerative medicine.
research The manipulation of the cedrol metabolism pathway by baricitinib and its immune interaction mechanism against chemotherapy-induced alopecia
research Proteomic analysis of hair shaft and nail plate.
Hair and nail proteins, mainly keratins, are crucial for structure and can indicate health issues.
research Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease
Nanomaterials could improve PCOS treatment by delivering drugs more effectively with fewer side effects.
research Effects of lncRNA MTC on protein expression in skin fibroblasts of Liaoning Cashmere goat based on iTRAQ technique
lncRNA MTC affects protein levels in goat skin cells, impacting hair growth.
research Transferosomes versus transethosomes for the dermal delivery for minoxidil: Preparation and in vitro/ex vivo appraisal
Minoxidil, a hair loss treatment, works better and has fewer side effects when put into tiny particles called transethosomes, especially those containing oleic acid.
research Optimization of finasteride nano-emulsion preparation by using chemometrics approaches (and/or Box-Behnken design and regresion model)
research مطالعه توزیع و تغییرات قندهای انتهایی گلیکوکانژوگیتها در طی تکامل فولیکول مو در رت با استفاده از فن لکتین هیستوشیمیایی
Glycoconjugate sugars are important for hair follicle development.
research Novel Insights into TSC22D Family Genes in Metabolic Diseases and Cancer
TSC22D genes are key in metabolic diseases and cancer, offering potential as treatment targets.
research Ultrastructure of two types of glandular hairs of salvia farinacea benth during development
Capitate trichomes have more endoplasmic reticulum and vacuoles, while peltate trichomes have more plastids and larger subcuticular spaces.
research Follicular Delivery of Nanocarriers to Improve Skin Disease Treatment
Nanocarriers improve skin disease treatment by targeting hair follicles effectively.
research Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research Targeted Self-Assembled anti-NFκB AuNCs-Aptamer Nanoplatform for Precise Theranostics via Tailored Follicle Regeneration
A new treatment using gold nanoclusters can safely reduce unwanted hair growth.
research Novel RNF113A Variant Underlying X‐Linked Trichothiodystrophy With Presumed Mosaicism in an Unaffected Mother
A new genetic variant causes trichothiodystrophy in two brothers, but their mother may carry it without showing symptoms.