July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
142 citations
,
September 2020 in “Journal of neurophysiology” Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
61 citations
,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
123 citations
,
November 2003 in “Neuroscience Letters” TRPV4 helps sense pressure in mouse skin.
24 citations
,
March 2008 in “Neuroscience Research” Cat paws have complex touch sensors for detailed sensory processing.
5 citations
,
July 2022 in “Journal of Clinical Medicine” Long COVID-19 patients with skin pain might have a nerve condition that responds to a medication called gabapentin.
11 citations
,
July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
April 2023 in “IntechOpen eBooks” Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.
1 citations
,
April 2025 in “Pigment Cell & Melanoma Research” Managing stress and nerve activity can help treat segmental vitiligo and white hair.
137 citations
,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
77 citations
,
September 2017 in “Journal of Investigative Dermatology” TRPV3 in skin cells causes inflammation and cell death.
2 citations
,
November 2025 in “Pharmaceutics” Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
19 citations
,
January 2014 in “Facial plastic surgery” Dermabrasion improves skin appearance by removing the top layer to promote healing.
December 2025 in “Nature Communications” Club-like receptors detect light touch but not whisking.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
201 citations
,
November 1964 in “Journal of neurophysiology” The cuneate nucleus has two main neuron types: relay neurons and interneurons.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
2 citations
,
January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
14 citations
,
January 2012 in “International Journal of Trichology” Hodgkin's lymphoma can show up as hair loss.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
110 citations
,
January 1983 in “Brain Research Reviews” Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
7 citations
,
July 2025 in “The Journal of Physiology” C-tactile nerves are sensitive to hair movement.
70 citations
,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
2 citations
,
October 2023 in “Science advances” Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
February 2026 in “Medicina” Hyaluronic Acid Profhilo® reduces skin inflammation and nerve-related pain in atopic dermatitis.
63 citations
,
February 2010 in “Journal of Neurophysiology” Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
May 2025 in “Journal of Clinical Medicine” Women with alopecia areata have poor blood flow, possibly due to nerve inflammation.