61 citations
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October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
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January 2006 in “International review of cytology” Vertebrate skin evolved to be more specialized and complex, especially in land animals.
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
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June 2001 in “Medical Electron Microscopy” Trichilemmal cysts may form from hair follicle outer root sheath growth.
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January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
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November 2020 in “Proceedings of the National Academy of Sciences” HoxC genes are crucial for normal hair and nail development.
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January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
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November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
January 2020 in “Journal of Entomology and Zoology Studies” Canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle.
June 2014 in “Experimental dermatology” The epidermis is crucial for hair growth.
126 citations
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January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Different keratin proteins are expressed in various epithelial cells at different stages, affecting cell structure and function.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.
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July 2008 in “Archives of Dermatological Research”
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January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
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November 1998 in “Experimental Cell Research” K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
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January 2018 in “Advances in experimental medicine and biology” Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
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August 2007 in “PLoS ONE” Myc changes chromatin in stem cells, causing them to leave their niche.
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December 2013 in “Journal of Cell Science” Keratin 79 cells help form and regenerate hair canals.
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January 2018 in “Development” Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
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September 2000 in “Journal of Investigative Dermatology” μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
150 citations
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May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
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February 1975 in “Journal of Cutaneous Pathology” Dermal cell activity increases during hair growth in rats.
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January 2020 Ift20 is essential for hair follicle function and skin cell movement.
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May 2008 in “Journal of Visualized Experiments” Mouse Epidermal Neural Crest Stem Cells can become various cell types.
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May 2008 in “Development” Activating β-catenin can turn skin cells into hair follicles.
August 2024 in “Microscopy Research and Technique” The study identifies the pheromone gland's location and structure in Endoclita vietnamensis, aiding future pest control methods.
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January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
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November 2002 in “Journal of Investigative Dermatology”