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A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.

The LEF-1 gene in cashmere goats was successfully cloned and analyzed, showing potential for improving cashmere production.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.

Patched1 helps prevent tumors by controlling cell growth.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Cantú syndrome may be linked to pituitary adenomas.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The Foxn1 gene is essential for normal nail and hair development.

The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Mutant Cx43 causes slower wound healing and hair growth issues in ODDD.

GLI2 activates GLI1, promoting skin tumor growth and hair development.

LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

FTase and GGTase-I are essential for skin keratinocyte health.

Glucocorticoid receptors help regulate genes important for skin health and hair growth.

The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.