January 2026 in “International Journal of Molecular Sciences” Hedgehog pathway inhibitors could be effective in treating melanoma.
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April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
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December 2024 in “International Journal of Molecular Sciences” Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.
20 citations
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December 1995 in “Veterinary Dermatology” Yorkshire Terriers with Colour Dilution Alopecia have reduced melanin and hair structure issues.
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October 2022 in “Cell Regeneration” A new mouse model effectively mimics vitiligo for research and drug testing.
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August 1969 in “Science” Melatonin causes weasels to grow white fur and become reproductively inactive.
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March 1989 in “Experimental Cell Research” Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
8 citations
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February 1968 in “Australian Journal of Zoology” The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.
Multiphoton microscopy helps understand and improve vitiligo treatments by visualizing skin cell changes.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
November 2025 in “Journal of Investigative Dermatology” Combining MMP-9 and JAK inhibitors can effectively prevent skin depigmentation in vitiligo.
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July 2025 in “Drug development & registration” A new algorithm accurately analyzes animal coat and skin colors quickly and easily.
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January 1992 in “Acta Histochemica” Porcine and human pilosebaceous units are very similar.
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September 2004 in “Experimental Dermatology” MC-1R is present in skin cells and may help reduce inflammation.
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January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
July 2025 in “Journal of Investigative Dermatology” 27 citations
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July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
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March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
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January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
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January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
Human hair color is determined by melanin types and genetic factors.
1 citations
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December 2024 in “Case Reports in Dermatology” Cyclophosphamide likely causes skin darkening by affecting hair follicles.
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August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
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June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
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October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Lemur hair color and density vary by environment, supporting theories on primate hair evolution.
March 2014 in “Institutional Repositories DataBase (IRDB)” Skin-derived stem cells could help treat skin aging and pigmentation issues.
24 citations
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March 2001 in “PubMed” In Freixo de Espada à Cinta, common skin conditions include melanocytic nevi, hemangiomas, and acne, with variations based on age and sex.
April 2025 in “Pharmacognosy Magazine” Compound Baqia Danshen Liniment may effectively treat vitiligo by improving skin and hair pigmentation and reducing inflammation.