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Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

The medicine Cyclosporin A might cause excessive hair growth by reducing a protein that controls hair growth.

The enzyme PA-PLA1α is important for proper hair follicle development.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.

A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.

Key genes affect cashmere quality differences between Jiangnan and Changthangi goats.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Pachyonychia congenita is linked to a keratin gene on chromosome 17.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

K6hf is a unique protein found only in a specific layer of hair follicles.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.

Cyclosporin promotes hair growth by boosting cell growth and reducing cell death.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Cyclosporin A helps hair grow by increasing certain growth factors.

Different gene mutations cause different types of ichthyosis, with some new mutations found.

Certain gene variations increase the risk of alopecia areata in Koreans.

Certain SPINK5 gene mutations are common in Israeli families with Comèl-Netherton syndrome.

Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

The vector successfully directed specific gene expression in hair follicles.

hsa_circ_0002980 can help stop liver cancer cells from growing and spreading.