83 citations
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October 1998 in “The American Journal of Human Genetics” A specific gene mutation causes complete hair loss in an Irish Traveller family.
81 citations
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February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
68 citations
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January 2013 in “BMC Pharmacology and Toxicology” Glibenclamide slows breast cancer cell growth by stopping cell division.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
61 citations
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September 2024 in “Micromachines” Electrospun nanofiber membranes are promising for non-invasive medical uses like tissue repair and health monitoring.
60 citations
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November 2023 in “Biology” Aging skin causes inflammation that affects the whole body.
58 citations
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November 2018 in “Cochrane library” Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.
54 citations
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March 2024 in “Journal of Medicinal Chemistry” N-oxides are important in medicine for improving drug properties and targeting.
53 citations
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January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
48 citations
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July 2023 in “Biomedicines” Hydrogel-forming microneedles are promising for safe, efficient, and controlled drug delivery through the skin.
48 citations
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July 2022 in “International Journal of Nanomedicine” Nanobiotechnology could improve chronic wound healing and reduce costs.
44 citations
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October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
40 citations
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July 2024 in “Bioengineering” 3D bioprinting holds promise for medicine but needs more research and clear regulations.
39 citations
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October 2012 in “Familial cancer” New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
36 citations
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August 2022 in “Frontiers in Cell and Developmental Biology” Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
36 citations
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October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
35 citations
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October 2019 in “Journal of pediatric health care” Children with darker skin tones can have specific skin conditions that need tailored treatments.
29 citations
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February 2021 in “Cancers” Ion channels play a key role in ovarian cancer growth and treatment resistance.
28 citations
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September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
27 citations
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August 2003 in “Anais Brasileiros de Dermatologia” Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
25 citations
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March 2021 in “Australasian Journal of Dermatology” Ustekinumab successfully treated a man's resistant skin condition when other treatments failed.
24 citations
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March 2024 in “Antioxidants” Ginger and cinnamon can help manage PCOS and related disorders by reducing oxidative stress and inflammation.
24 citations
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July 2023 in “Journal of Functional Biomaterials” Bubble-based systems show promise for precise, targeted drug delivery and diagnosis, especially in cancer treatment.
24 citations
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May 2022 in “Frontiers in Endocrinology” Activating brown fat may help manage PCOS symptoms.
22 citations
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April 2021 in “Human Cell” MicroRNAs may help diagnose and treat hair loss disorders.
21 citations
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August 2024 in “Journal of Clinical Medicine” Proper nutrition can help balance the immune system and reduce allergies.
21 citations
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August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
21 citations
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January 2022 in “Pharmaceutics” Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.